Evidence map›Paper›PMID 33852037›Full record

ArticleStrahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]2021

Total body irradiation of bone marrow transplant using helical TomoTherapy with a focus on the quality of dose contribution at junction target volumes.

N V N Madhusudhana Sresty, Deleep Gudipudi, A Krishnam Raju, T Anil Kumar, V R P Lakshmi, G Srikanth, M Narasimha

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In one paragraph

Article in Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Automatic planning of the lower extremities for total marrow irradiation using volumetric modulated arc therapy.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2023
    Article
  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

N V N Madhusudhana SrestyDepartment of Radiotherapy, Basavatarakam Indo American Cancer Hospital & Research Institute, Hyderabad, India. srestybarc@gmail.com.ORCID http://orcid.org/0000-0003-2921-7409
Deleep GudipudiDepartment of Radiotherapy, Basavatarakam Indo American Cancer Hospital & Research Institute, Hyderabad, India.
A Krishnam RajuDepartment of Radiotherapy, Basavatarakam Indo American Cancer Hospital & Research Institute, Hyderabad, India.
T Anil KumarDepartment of Radiotherapy, Basavatarakam Indo American Cancer Hospital & Research Institute, Hyderabad, India.
V R P LakshmiDepartment of Radiotherapy, Basavatarakam Indo American Cancer Hospital & Research Institute, Hyderabad, India.
G SrikanthDepartment of Radiotherapy, Basavatarakam Indo American Cancer Hospital & Research Institute, Hyderabad, India.
M NarasimhaDepartment of Radiotherapy, Basavatarakam Indo American Cancer Hospital & Research Institute, Hyderabad, India.
Basavatarakam Indo American Cancer Hospital and Research Institute · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTotal body irradiation (TBI) can be safely delivered on TomoTherapy (Accuray, Sunnyvale, CA, USA) in both pediatric and adult patients with proper imaging and planning despite the length constraint of 135 cm. To overcome this limitation, two CT (Computed Tomography) scans (CT1& CT2) are taken in patients above 135 cm in height. Adequate junction dose coverage is important in TBI. Presently, there is no clinical report with a focus on the quality of dose distribution at the CT junction in view of the guidelines on quality of coverage from the RTOG. Hence, our main objectives were to evaluate the dose distribution and quality of coverage at the junction in 16 patients who received TBI using TomoTherapy.

methodsPTV(upper) and PTV(lower) along with a junction were created on CT1 and CT2, respectively. Subsequently, the 10 cm junction in the thigh region was divided into five target volumes of 2 cm thickness with dose prescription ranging from 10 to 90% to deliver a total dose equal to 100% when fused.

resultsThe D

conclusionSince junction-based planning was required for most TBI patients, it is essential to evaluate the quality of dose coverage in the junction for better TBI plans.

Indexed as

Bone Marrow TransplantationWhole-Body IrradiationAdultBone MarrowChildHumansOrgans at RiskRadiotherapy DosageRadiotherapy Planning, Computer-AssistedTomography, X-Ray ComputedYoung AdultALLJunction doseModulation FactorNHLPitchQuality of coverage

Identifiers

PMID33852037
OpenAlexW3155858953

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.