ArticleInvestigative ophthalmology & visual science2021
Rapid Myopic Progression in Childhood Is Associated With Teenage High Myopia.
Article in Investigative ophthalmology & visual science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Bioelectronic interfaces for restoring vision pathways.Materials today. Bio · 2026Review
- The application of artificial intelligence in myopia prediction for children and adolescents: a review.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Review
- Cost-Effectiveness Analysis of Low-Dose Atropine Eye Drops (0.01%) for the Treatment of Myopia in Children: A United Kingdom Perspective.PharmacoEconomics · 2026Article
- Trends in childhood myopia over a 5-year interval: Korea national health and nutrition examination survey 2016 and 2021.Japanese journal of ophthalmology · 2026Article
- Deep Learning Prediction of Childhood Myopia Progression Using Fundus Image and Refraction Data.JAMA network open · 2026Article
- Quantitative color fundus photography parameters as potential biomarkers of axial length progression: evidence from a machine learning cohort study.Frontiers in cell and developmental biology · 2026Article
- Choroidal thickness and peripapillary RNFL in relation to axial length and progression in myopic children.Frontiers in bioengineering and biotechnology · 2026Article
- Axial length changes and baseline predictors over five years in children treated with orthokeratology lenses: a retrospective cohort study.Frontiers in bioengineering and biotechnology · 2026Article
- Three-year surveillance of myopia trends and urban-rural disparities among schoolchildren in a Coastal City of Southern China.Frontiers in public health · 2026Article
- Trajectories and predictors of spherical equivalent among multiethnic school-aged children in Southwest China: a 2.5-year cohort study.BMJ open · 2025Article
- Longitudinal changes in macular curvature and axial elongation in school children.International journal of retina and vitreous · 2025Article
- Optimizing myopia screening referral guidelines for children aged 4 to 18 based on non-cycloplegic indicators.BMC ophthalmology · 2025Article
- Axial elongation as a marker to identify obvious myopic shift in non-myopic eyes of Chinese children.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2025Article
- A Self-Generated Electricity-Driven Sclera reinforcement bionic piezoelectric patch for Management of High Myopia.Journal of nanobiotechnology · 2025Article
- Key strategies to reduce the global burden of myopia: consensus from the international myopia summit.The British journal of ophthalmology · 2025Review
- Association of Retinal Microvasculature With Myopia Progression in Children: The Hong Kong Children Eye Study.Investigative ophthalmology & visual science · 2025Article
- The Impact of School Education on High Myopia in Children and Adolescents.International journal of general medicine · 2025Article
- Causal relationship between multiple types of food intake and myopia: a Mendelian randomization study.International journal of ophthalmology · 2025Article
- Prevention and management of childhood progressive myopia: National consensus guidelines.Indian journal of ophthalmology · 2023Article
- Deep learning system to predict the 5-year risk of high myopia using fundus imaging in children.NPJ digital medicine · 2023Article
Corrections and comments
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Authors and funding
11 authors.
Funding
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Abstract
Purpose: The purpose of this study was to evaluate the association of childhood progression of spherical equivalent (SE) with high myopia (HM) in teenagers in the Singapore Cohort of Risk factors for Myopia (SCORM). Methods: We included 928 SCORM children followed over a mean follow-up of 6.9 ± 1.0 years from baseline (6-11 years old) until their teenage years (12-19 years old). Cycloplegic autorefraction and axial length (AL) measurements were performed yearly. The outcomes in teenagers were HM (SE ≤ -5 diopter [D)], AL ≥ 25 mm, SE and AL. Three-year SE and AL progression in childhood and baseline SE and AL with outcomes were evaluated using multivariable logistic or linear regression models, with predictive performance of risk factors assessed using the area under the curve (AUC). Results: At the last visit, 9.8% of teenagers developed HM and 22.7% developed AL ≥ 25 mm. In multivariate regression analyses, every -0.3 D/year increase in 3-year SE progression and every 0.2 mm/year increase in 3-year AL progression were associated with a -1.14 D greater teenage SE and 0.52 mm greater teenage AL (P values < 0.001). The AUC (95% confidence interval [CI]) of a combination of 3-year SE progression and baseline SE for teenage HM was 0.97 (95% CI = 0.95 - 0.98). The AUC of 3-year AL progression and baseline AL for teenage AL ≥ 25 mm was 0.91 (95% CI = 0.89 - 0.94). Conclusions: Three-year myopia progression in childhood combined with baseline SE or AL were good predictors of teenage HM. Clinicians may use this combination of factors to guide timing of interventions, potentially reducing the risk of HM later in life.
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