ArticleJournal of medical virology2021
Axonal Guillain-Barre syndrome associated with SARS-CoV-2 infection in a child.
Article in Journal of medical virology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.
- Neurological Manifestations of Coronavirus Disease 2019 and Mpox in Pediatric Patients and Their Management: A State-of-the-Art Systematic Review.Pediatric neurology · 2023Pooled it
- Guillain-Barré Syndrome Associated with SARS-CoV-2 in Two Pediatric Patients.Sultan Qaboos University medical journal · 2023Article
- Guillan-barre syndrome during COVID-19 pandemic: a case series from Syria.Annals of medicine and surgery (2012) · 2023Article
- Two case reports and a literature review of typical GBS and rare GBS variants associated with COVID-19.Archives de pediatrie : organe officiel de la Societe francaise de pediatrie · 2023Review
- Guillain-Barré Syndrome Associated with COVID-19: Is There A Causal Relation or Just A Coincidence?Noro psikiyatri arsivi · 2023Article
- Childhood Guillain-Barre syndrome in the SARS-CoV-2 era: Is there any causative relation?Clinical case reports · 2022Article
- Do not miss Bickerstaff encephalitis as a complication of SARS-CoV-2 vaccines.Radiology case reports · 2022Article
- Possible association between Guillain-Barré syndrome and SARS-CoV-2 infection in children: A case report and literature review.Experimental and therapeutic medicine · 2022Article
- Guillain-Barre syndrome (GBS) associated with COVID-19 infection that resolved without treatment in a child.BMJ case reports · 2022Article
- Spectrum of neuroimaging mimics in children with COVID-19 infection.Biomedical journal · 2022Review
- Consider differentials before diagnosing COVID-19 associated polyradiculitis.European journal of translational myology · 2022Article
- Guillain-Barré syndrome is immunogenic in SARS-CoV-2 infected.Journal of medical virology · 2022Article
- Diagnose SARS-CoV-2 associated Guillain-Barre syndrome upon appropriate criteria and after exclusion of differentials.Journal of medical virology · 2021Article
- Axonal Guillain-Barre syndrome associated with SARS-CoV-2 infection in a child.Journal of medical virology · 2021Article
- [Guillain Barré syndrome in the paediatric population. Consequence of active infection or long Covid?]Revista colombiana de reumatologiaReview
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The relation between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and demyelinating Guillain-Barre syndrome (GBS) has been defined. We aim to report the clinical features of a child with axonal GBS associated with SARS-CoV-2. A 6-year-old male presented with symmetric ascending paralysis progressed over a 4-day course and 2 days of fever. He had bilateral lower and upper limb flaccid weakness of 1/5 with absent deep tendon reflexes. He had severe respiratory muscle weakness requiring invasive mechanical ventilation. On admission, SARS-CoV-2 returned as positive by real-time polymerase chain reaction on a nasopharyngeal swab. Cerebrospinal fluid analysis showed elevated protein without pleocytosis. He was diagnosed with GBS associated with SARS-CoV-2 infection. The nerve conduction study was suggestive of acute motor axonal neuropathy. Ten consecutive therapeutic plasma exchange sessions with 5% albumin replacement followed by four sessions on alternate days were performed. On Day 12, methylprednisolone (30 mg/kg/day for 5 days) was given. On Day 18, intravenous immunoglobulin (2 g/kg/day) was given and repeated 14 days after due to severe motor weakness. On Day 60, he was discharged from the hospital with weakness of neck flexor and extensor muscles of 3/5 and the upper limbs and the lower limbs of 2/5 on home-ventilation. Our patient is considered to be the youngest patient presenting with a possible para-infectious association between axonal GBS and SARS-CoV-2 infection. The disease course was severe with a rapid progression, an earlier peak, and prolonged duration in weakness as expected in axonal GBS.
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