Evidence map›Paper›PMID 33851285›Full record

ReviewCurrent osteoporosis reports2021

Do Interactions of Vitamin D

Jessica L Pierce, Daniel S Perrien

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Current osteoporosis reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jessica L PierceDivision of Endocrinology, Metabolism, and Lipids, Department of Medicine, Emory University School of Medicine, 101 Woodruff Circle, WMRB 1027, Atlanta, GA, 30232, USA.
Daniel S PerrienDivision of Endocrinology, Metabolism, and Lipids, Department of Medicine, Emory University School of Medicine, 101 Woodruff Circle, WMRB 1027, Atlanta, GA, 30232, USA. dperrie@emory.edu.ORCID 0000-0002-5488-3932

Funding

The contribution of innate immunity to heterotopic ossification in fibrodysplasia ossificans progressivaR01AR073874 · NIAMS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI PERRIEN, DANIEL S · 2018 to 2022
$2.5M
NIAMS NIH HHS R01 AR073874
6 · The paper itself

Abstract

purpose of reviewFibrodysplasia ossificans progressiva (FOP) is a debilitating rare disease known for episodic endochondral heterotopic ossification (HO) caused by gain-of-function mutations in ACVR1/ALK2. However, disease severity varies among patients with identical mutations suggesting disease-modifying factors, including diet, may have therapeutic implications. The roles of vitamin D RECENT

findingsIn vitro and in vivo studies suggest vitamin D suppresses inflammation, while clinical studies suggest that vitamin D

Indexed as

ActivinsAnimalsBone Morphogenetic ProteinsCholecalciferolChondrogenesisHumansMyositis OssificansSignal Transductionactivin AActivinsBone Morphogenetic ProteinsCholecalciferolALK2ChondrogenesisInflammationMuscle repairSkeletal muscleVDR

Identifiers

PMID33851285
PMCPMC8515998

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.