ReviewPediatric nephrology (Berlin, Germany)2021
Renovascular hypertension in pediatric patients: update on diagnosis and management.
Review in Pediatric nephrology (Berlin, Germany), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.
- Cardiovascular implications in adolescent and young adult hypertension.Reviews in cardiovascular medicine · 2022Pooled it
- Aorto-Renal Dysplasia in Childhood: The Overlap of Neurofibromatosis Type 1 and Pediatric Renovascular Hypertension.Current hypertension reports · 2026Review
- Spontaneous renal artery thrombosis causing circulatory insufficiency in a newborn- a case report.BMC pediatrics · 2025Article
- Approach to pediatric renovascular hypertension.Childhood kidney diseases · 2025Review
- Pediatric Renovascular Hypertension: Diagnosis and Management.Seminars in interventional radiology · 2025Review
- Complex equilibrium involving aldosterone underlies the pathophysiology of renovascular hypertension.Clinical pediatric endocrinology : case reports and clinical investigations : official journal of the Japanese Society for Pediatric Endocrinology · 2025Article
- A narrative review of the role of renal artery intervention in renovascular hypertension.Frontiers in surgery · 2025Review
- Renal Artery Stenosis and Mid-Aortic Syndrome in Children-A Review.Journal of clinical medicine · 2024Review
- Review
- Cardiovascular outcomes improve in children with renovascular hypertension following endovascular and surgical interventions.Pediatric nephrology (Berlin, Germany) · 2024Observational
- A rare cause of posterior reversible encephalopathy syndrome: Acute lymphoblastic leukemia.Clinical case reports · 2023Article
- Outcomes of percutaneous transluminal renal angioplasty for pediatric renovascular hypertension: a 12-year retrospective single-center experience.Translational pediatrics · 2023Article
- Multimodal imaging approach in hyponatremic hypertensive syndrome. A rare case of pediatric unilateral hypoplasia of the main renal artery combined itself with stenosis and review of literature.Radiology case reports · 2023Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Renovascular hypertension (RVH) is defined as an elevated blood pressure caused by kidney hypoperfusion, generally as a result of anatomic stenosis of the renal artery with consequent activation of the Renin Angiotensin-Aldosterone System. The main causes include genetic and inflammatory disorders, extrinsic compression, and idiopathic alterations. RVH is often asymptomatic and should be suspected in any child with refractory hypertension, especially if other suggestive findings are present, including those with severe hypertension, abdominal bruit, and abrupt fall of glomerular filtration rate after administration of angiotensin-converting enzyme inhibitors or angiotensin-receptor blockers. There is a consensus that digital subtraction angiography is the gold standard method for the diagnosis of RVH. Nevertheless, the role of non-invasive imaging studies such as Doppler ultrasound, magnetic resonance angiography, or computed tomographic angiography remains controversial, especially due to limited pediatric evidence. The therapeutic approach should be individualized, and management options include non-surgical pharmacological therapy and revascularization with percutaneous transluminal renal angioplasty (PTRA) or surgery. The prognosis is related to the procedure performed, and PTRA has a higher restenosis rate compared to surgery, although a decreased risk of complications. This review summarizes the causes, physiopathology, diagnosis, treatment, and prognosis of RVH in pediatric patients. Further studies are required to define the best approach for RVH in children.
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