Evidence map›Paper›PMID 33851099›Full record

ArticleiScience2021

Adhesion G protein-coupled receptor VLGR1/ADGRV1 regulates cell spreading and migration by mechanosensing at focal adhesions.

Deva K Kusuluri, Baran E Güler, Barbara Knapp, Nicola Horn, Karsten Boldt, Marius Ueffing, Gabriela Aust, Uwe Wolfrum

Open access · goldAbstract read
In one paragraph

Article in iScience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 44 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Adhesion G protein-coupled receptors.Pharmacological reviews · 2026
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. HGG advances · 2023
    Article
  19. Successful large gene augmentation of USH2A with non-viral episomal vectors.Molecular therapy : the journal of the American Society of Gene Therapy · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Deva K KusuluriInstitute of Molecular Physiology, Molecular Cell Biology, Johannes Gutenberg University, Hanns-Dieter-Hüsch-Weg 17, 55099 Mainz, Germany.
Baran E GülerInstitute of Molecular Physiology, Molecular Cell Biology, Johannes Gutenberg University, Hanns-Dieter-Hüsch-Weg 17, 55099 Mainz, Germany.
Barbara KnappInstitute of Molecular Physiology, Molecular Cell Biology, Johannes Gutenberg University, Hanns-Dieter-Hüsch-Weg 17, 55099 Mainz, Germany.
Nicola HornMedical Proteome Center, Institute for Ophthalmic Research, Eberhard Karls University of Tuebingen, 72074 Tuebingen, Germany.
Karsten BoldtMedical Proteome Center, Institute for Ophthalmic Research, Eberhard Karls University of Tuebingen, 72074 Tuebingen, Germany.
Marius UeffingMedical Proteome Center, Institute for Ophthalmic Research, Eberhard Karls University of Tuebingen, 72074 Tuebingen, Germany.
Gabriela AustClinic of Visceral, Transplantation, Thoracic and Vascular Surgery & Clinic of Orthopedics, Traumatology and Plastic Surgery, Department of Surgery Research Laboratory, Leipzig University, 04301 Leipzig, Germany.
Uwe WolfrumInstitute of Molecular Physiology, Molecular Cell Biology, Johannes Gutenberg University, Hanns-Dieter-Hüsch-Weg 17, 55099 Mainz, Germany.
Johannes Gutenberg University Mainz · DEUniversity of Tübingen · DELeipzig University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

VLGR1 (very large G protein-coupled receptor-1) is by far the largest adhesion G protein-coupled receptor in humans. Homozygous pathologic variants of

Indexed as

BiomoleculesCell BiologyMolecular Biology

Identifiers

PMID33851099
PMCPMC8024656
OpenAlexW3135178773

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.