Evidence map›Paper›PMID 33851075›Full record

ArticleNorthern clinics of Istanbul2021

Characteristics and clinical outcome of pT1a-b node-negative breast cancer.

Abdilkerim Oyman, Mustafa Basak, Hatice Odabas, Melike Ozcelik

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Article in Northern clinics of Istanbul, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

4 authors.

Abdilkerim OymanDepartment of Medical Oncology, University of Health Sciences Umraniye Training and Research Hospital, Istanbul, Turkey.
Mustafa BasakDepartment of Medical Oncology, Dr. Lutfi Kirdar Kartal Training and Research Hospital, Istanbul, Turkey.
Hatice OdabasDepartment of Medical Oncology, Dr. Lutfi Kirdar Kartal Training and Research Hospital, Istanbul, Turkey.
Melike OzcelikDepartment of Medical Oncology, University of Health Sciences Umraniye Training and Research Hospital, Istanbul, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTumor size, along with other clinicopathological characteristics, has a prognostic role in breast cancer. Recurrence risk tends to rise as tumor size increases. Early T-stage portends a good prognosis. We aimed to investigate the recurrence-free interval rates of T1abN0 group of early breast cancer.

methodsPatients diagnosed with pT1a and T1b, lymph node metastasis-negative breast cancer were included in the study. Clinicopathologic characteristics including recurrence, distant metastasis, and final status of the patients were obtained retrospectively from the patient files.

resultsA total of 84 patients included. Twenty-six patients (31%) had T1a and 58 patients (69%) had T1b tumors. The 5-year distant relapse-free survival (DRFS) rate of T1ab tumors was 95.2%. The DRFS rate of T1a tumors was 96.2%, while the rate of T1b tumors was 94.8% (p=0.555). The 5-year RFS rate of T1ab tumors was 90.5%. The RFS rate of T1a tumors was 84.6%, whereas the rate of T1b tumors was 93.1% (p=0.359). The 5-year DRFS rate of hormone receptor positive group was 97%, Her-2 positive group was 81.8%, and triple negative group was 100% (p=0.041). The 5-year RFS rate of the hormone receptor positive group was 97%, Her-2 positive group was 72.7%, and triple negative group was 57.1% (p=0.001).

conclusionThe results of the study provided that both T1a and T1b tumors have a good and similar prognosis.

Indexed as

Distant relapse-free survivalearly breast cancerT1ab

Identifiers

PMID33851075
PMCPMC8039097

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