ArticleAdvances in radiation oncology
An International Expert Survey on the Indications and Practice of Radical Thoracic Reirradiation for Non-Small Cell Lung Cancer.
Article in Advances in radiation oncology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
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Who cites it
39 citing papers in PubMed, 56 citations in OpenAlex.
- Grid Radiation Therapy Based on Multileaf Collimator for Neoadjuvant Treatment of Large-Volume Intrahepatic Cholangiocarcinoma: A Case Report.Advances in radiation oncology · 2026Article
- Modeling Time-Dependent Recovery to Improve Esophagitis Prediction in Thoracic Reirradiation.International journal of radiation oncology, biology, physics · 2026Article
- MR-guided stereotactic radiosurgery of an intracardiac tumoral thrombus using comprehensive motion management.Clinical and translational radiation oncology · 2026Article
- Re-evaluating previous dose and allowing increasing recovery (REPAIR): study protocol for a thoracic reirradiation phase I dose escalation trial.BMC cancer · 2026Article
- A dedicated institutional clinical workflow and peer-review meeting for reirradiation.Technical innovations & patient support in radiation oncology · 2026Article
- Landmark-guided deformable image registration for accurate cumulative dose evaluation in lung reirradiation.Physics and imaging in radiation oncology · 2026Article
- Treatment planning for lung cancer reirradiation accounting for previously delivered dose.Physics and imaging in radiation oncology · 2026Article
- Cumulative oesophageal dose and risk of high-grade toxicity in thoracic re-irradiation: a dose/toxicity analysis.Clinical and translational radiation oncology · 2026Review
- Standardising image registration and dose mapping for thoracic reirradiation: A national multi-centre benchmarking study.Physics and imaging in radiation oncology · 2026Article
- Thoracic reirradiation clinical and technical practices: a survey from the reirradiation Collaborative Group (ReCOG).Clinical and translational radiation oncology · 2026Article
- Case report: Helical tomotherapy-based whole lung irradiation with simultaneous integrated boost for pulmonary metastatic Ewing's sarcoma: a case series report and feasibility analysis.Frontiers in oncology · 2026Article
- Isotoxic stereotactic reirradiation for recurrent pelvic cancers.Physics and imaging in radiation oncology · 2026Article
- Case Report: Innovative radiotherapy strategies in advanced colon cancer with oligometastasis: a case of online adaptive radiotherapy and lattice stereotactic re-irradiation.Frontiers in oncology · 2026Article
- A prospective audit of thoracic reirradiation practice and peer-review in a high-volume academic center.Technical innovations & patient support in radiation oncology · 2025Article
- Multi-institutional virtual peer review for reirradiation: dedicated workflow and one-year results.Technical innovations & patient support in radiation oncology · 2025Article
- Feasibility and efficacy of hypofractionated proton reirradiation for recurrent lung cancer.International journal of particle therapy · 2025Article
- Re-irradiation of recurrent lung tumours: Associations between dose and 2-year survival.Clinical and translational radiation oncology · 2025Article
- Efficacy and safety of twice-daily accelerated hyperfractionated re-irradiation for thoracic malignancies.Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology · 2025Article
- Improving reirradiation of recurrent non-small cell lung cancer through non-coplanar beam arrangements.Physics and imaging in radiation oncology · 2025Article
- Reirradiation: Evaluation of the occurrence and type in cancer treatment for lung - 2024.Technical innovations & patient support in radiation oncology · 2025Article
Corrections and comments
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Authors and funding
18 authors at 14 institutions in 7 countries.
Funding
Abstract
purposeThoracic reirradiation for non-small cell lung cancer with curative intent is potentially associated with severe toxicity. There are limited prospective data on the best method to deliver this treatment. We sought to develop expert consensus guidance on the safe practice of treating non-small cell lung cancer with radiation therapy in the setting of prior thoracic irradiation. METHODS AND MATERIALS: Twenty-one thoracic radiation oncologists were invited to participate in an international Delphi consensus process. Guideline statements were developed and refined during 4 rounds on the definition of reirradiation, selection of appropriate patients, pretreatment assessments, planning of radiation therapy, and cumulative dose constraints. Consensus was achieved once ≥75% of respondents agreed with a statement. Statements that did not reach consensus in the initial survey rounds were revised based on respondents' comments and re-presented in subsequent rounds.
resultsFifteen radiation oncologists participated in the 4 surveys between September 2019 and March 2020. The first 3 rounds had a 100% response rate, and the final round was completed by 93% of participants. Thirty-three out of 77 statements across all rounds achieved consensus. Key recommendations are as follows: (1) appropriate patients should have a good performance status and can have locally relapsed disease or second primary cancers, and there are no absolute lung function values that preclude reirradiation; (2) a full diagnostic workup should be performed in patients with suspected local recurrence and; (3) any reirradiation should be delivered using optimal image guidance and highly conformal techniques. In addition, consensus cumulative dose for the organs at risk in the thorax are described.
conclusionsThese consensus statements provide practical guidance on appropriate patient selection for reirradiation, appropriate radiation therapy techniques, and cumulative dose constraints.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.