Evidence map›Paper›PMID 33850982›Full record

ArticleData in brief2021

ADC, D, f dataset calculated through the simplified IVIM model, with MGMT promoter methylation, age, and ECOG, in 38 patients with wildtype IDH glioblastoma.

Pejman Jabehdar Maralani, Sten Myrehaug, Hatef Mehrabian, Aimee Km Chan, Max Wintermark, Chris Heyn, John Conklin, Benjamin M Ellingson, Saba Rahimi, Angus Z Lau and 12 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Data in brief, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Biomaterial-basedCancer pathogenesis and therapy · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Pejman Jabehdar MaralaniDepartment of Medical Imaging, Sunnybrook Health Sciences Center, University of Toronto, Toronto, ON, Canada.
Sten MyrehaugDepartment of Radiation Oncology, Sunnybrook Health Sciences Center, University of Toronto, Toronto, ON, Canada.
Hatef MehrabianDepartment of Radiation Oncology, Sunnybrook Health Sciences Center, University of Toronto, Toronto, ON, Canada.
Aimee Km ChanDepartment of Medical Imaging, Sunnybrook Health Sciences Center, University of Toronto, Toronto, ON, Canada.
Max WintermarkDepartment of Radiology, Stanford University, Stanford, CA, United States.
Chris HeynDepartment of Medical Imaging, Sunnybrook Health Sciences Center, University of Toronto, Toronto, ON, Canada.
John ConklinDepartment of Radiology, Massachusetts General Hospital, Boston, MA, United States.
Benjamin M EllingsonDepartment of Radiological Sciences and Psychiatry, University of California Los Angeles, Los Angeles, CA, United States.
Saba RahimiDepartment of Biomedical Engineering, University of Toronto, Toronto, ON, Canada.
Angus Z LauDepartment of Medical Biophysics, Sunnybrook Research Institute, University of Toronto, Toronto, ON, Canada.
Chia-Lin TsengDepartment of Radiation Oncology, Sunnybrook Health Sciences Center, University of Toronto, Toronto, ON, Canada.
Hany SolimanDepartment of Radiation Oncology, Sunnybrook Health Sciences Center, University of Toronto, Toronto, ON, Canada.
Jay DetskyDepartment of Radiation Oncology, Sunnybrook Health Sciences Center, University of Toronto, Toronto, ON, Canada.
Shadi DaghighiDepartment of Medical Imaging, Sunnybrook Health Sciences Center, University of Toronto, Toronto, ON, Canada.
Julia KeithDepartment of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada.
David G MunozDepartment of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada.
Sunit DasDepartment of Surgery, Division of Neurosurgery, University of Toronto, Toronto, ON, Canada.
Eshetu G AtenafuDepartment of Biostatistics, University Health Network, Toronto, ON, Canada.
Nir LipsmanDepartment of Surgery, Division of Neurosurgery, University of Toronto, Toronto, ON, Canada.
James PerryDepartment of Medicine, Division of Neurology, University of Toronto, Toronto, ON, Canada.
Greg StaniszDepartment of Medical Biophysics, Sunnybrook Research Institute, University of Toronto, Toronto, ON, Canada.
Arjun SahgalDepartment of Radiation Oncology, Sunnybrook Health Sciences Center, University of Toronto, Toronto, ON, Canada.

Funding

UCLA SPORE in Brain CancerP50CA211015 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI David A. Nathanson · 2017 to 2026
$25.2M
NCI NIH HHS P50 CA211015
6 · The paper itself

Abstract

Patients undergoing standard chemoradiation post-resection had MRIs at radiation planning and fractions 10 and 20 of chemoradiation. MRIs were 1.5T and 3D T2-FLAIR, pre- and post-contrast 3D T1-weighted (T1) and echo planar DWI with three b-values (0, 500, and 1000s/mm

Indexed as

ADCDiffusion coefficientGlioblastomaOverall survivalPerfusion fractionProgression free survivalRecurrenceSimplified IVIM

Identifiers

PMID33850982
PMCPMC8039816

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.