Evidence map›Paper›PMID 33850693›Full record

ArticleNanotheranostics2021

Long circulating tracer tailored for magnetic particle imaging.

Sitong Liu, Andreina Chiu-Lam, Angelie Rivera-Rodriguez, Ryan DeGroff, Shehaab Savliwala, Nicole Sarna, Carlos M Rinaldi-Ramos

Abstract read
In one paragraph

Article in Nanotheranostics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed.

  1. Article
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  4. Review
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  6. Article
  7. Review
  8. Article
  9. Article
  10. Flame-Made Doped Iron Oxide Nanoparticles as Tracers for Magnetic Particle Imaging.Chemistry of materials : a publication of the American Chemical Society · 2025
    Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Review
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sitong LiuDepartment of Chemical Engineering, University of Florida, Gainesville, FL 32611, USA.
Andreina Chiu-LamDepartment of Chemical Engineering, University of Florida, Gainesville, FL 32611, USA.
Angelie Rivera-RodriguezJ. Crayton Pruitt Family Department of Biomedical Engineering, University of Florida, Gainesville, FL 32611-6131, USA.
Ryan DeGroffJ. Crayton Pruitt Family Department of Biomedical Engineering, University of Florida, Gainesville, FL 32611-6131, USA.
Shehaab SavliwalaDepartment of Chemical Engineering, University of Florida, Gainesville, FL 32611, USA.
Nicole SarnaJ. Crayton Pruitt Family Department of Biomedical Engineering, University of Florida, Gainesville, FL 32611-6131, USA.
Carlos M Rinaldi-RamosDepartment of Chemical Engineering, University of Florida, Gainesville, FL 32611, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Superparamagnetic iron oxide nanoparticle (SPION) tracers possessing long blood circulation time and tailored for magnetic particle imaging (MPI) performance are crucial for the development of this emerging molecular imaging modality. Here, single-core SPION MPI tracers coated with covalently bonded polyethyelene glycol (PEG) brushes were obtained using a semi-batch thermal decomposition synthesis with controlled addition of molecular oxygen, followed by an optimized PEG-silane ligand exchange procedure. The physical and magnetic properties, MPI performance, and blood circulation time of these newly synthesized tracers were compared to those of two commercially available SPIONs that were not tailored for MPI but are used for MPI: ferucarbotran and PEG-coated Synomag

Indexed as

Contrast MediaMagnetite NanoparticlesAnimalsFemaleMiceMice, Inbred BALB CMolecular ImagingContrast MediaMagnetite Nanoparticlesiron oxide nanoparticleslong circulating tracermagnetic particle imaging

Identifiers

PMID33850693
PMCPMC8040827

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.