Evidence map›Paper›PMID 33850577›Full record

ArticleJournal of arrhythmia2021

Safety and efficacy of cryoballoon ablation for the treatment of paroxysmal and persistent AF in a real-world global setting: Results from the Cryo AF Global Registry.

Kyoung Ryul Julian Chun, Ken Okumura, Fernando Scazzuso, Young Keun On, Fred J Kueffer, Kendra M Braegelmann, Surinder Kaur Khelae, Fawzia Al-Kandari, Csaba Földesi, Cryo Global Registry Investigators

Abstract read
In one paragraph

Article in Journal of arrhythmia, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Real-world experience with the pentaspline pulsed field ablation system: one-year outcomes of the FARADISE registry.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2025
    Observational
  7. Article
  8. Article
  9. Impact of atrial fibrillation diagnosis-to-ablation time on 24-month efficacy and safety outcomes in the Cryo Global Registry.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2025
    Observational
  10. Article
  11. Article
  12. Article
  13. Article
  14. Pulsed field ablation and cryoballoon ablation for pulmonary vein isolation: insights on efficacy, safety and cardiac function.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2024
    Article
  15. Regional variations in patient selection and procedural characteristics for cryoballoon ablation of atrial fibrillation in the cryo global registry.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2024
    Article
  16. Article
  17. Review
  18. Atrial fibrillation cryoablation is an effective day case treatment: the UK PolarX vs. Arctic Front Advance experience.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2023
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Kyoung Ryul Julian ChunCardioangiologisches Centrum Bethanien Frankfurt Germany.
Ken OkumuraSaiseikai Kumamoto Hospital Kumamoto Japan.
Fernando ScazzusoInstitituo Cardiovascular Buenos Aires (ICBA) Buenos Aires Argentina.
Young Keun OnDivision of Cardiology Department of Internal Medicine Heart Vascular and Stroke Institute Samsung Medical Center Sungkyunkwan University School of Medicine Seoul Republic of Korea.
Fred J KuefferMedtronic, Inc Minneapolis MN USA.
Kendra M BraegelmannMedtronic, Inc Minneapolis MN USA.
Surinder Kaur KhelaeInstitut Jantung Negara - National Heart Institute Kuala Lumpur Malaysia.
Fawzia Al-KandariChest Disease Hospital Kuwait.
Csaba FöldesiGottsegen György Országos Kardiológiai Intézet Budapest Hungary.ORCID https://orcid.org/0000-0002-5033-117X
Cryo Global Registry Investigators

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCryoballoon ablation is a commonly used approach to treat patients with atrial fibrillation (AF).

objectivesReport on the safety and efficacy of cryoballoon ablation for the treatment of AF in the largest global cohort of cryoablated patients prospectively studied within a single registry.

methodsThe

resultsDuring this evaluation window, 2922 subjects completed an index cryoballoon procedure, and 1440 completed 12 month follow-up. The cohort was 61 ± 12 years of age, 36.3% female, and 78.7% PAF. Serious device- and procedure-related adverse event rates were 1.5% and 3.4%, respectively. Freedom from AF/AFL/AT after the 90 day blanking period was 86.4% (95% CI: 84.3%-88.3%) in patients with PAF and 70.9% (95% CI: 64.6%-76.4%) in patients with PsAF. Freedom from AF/AFL/AT in first-line PAF and PsAF was 90.0% (95% CI: 86.4%-92.7%) and 72.9% (95% CI: 58.6%-83.0%) at 12 months, respectively.

conclusionsThe

Indexed as

antiarrhythmic drugatrial fibrillationcatheter ablationcryoballoonpulmonary vein isolation

Identifiers

PMID33850577
PMCPMC8021998

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.