Evidence map›Paper›PMID 33850451›Full record

ArticleReproductive medicine and biology2021

Laser-assisted hatching on clinical and neonatal outcomes in patients undergoing single vitrified Blastocyst transfer: A propensity score-matched study.

Yuji Endo, Shingo Mitsuhata, Momoko Hayashi, Yoshitaka Fujii, Hiroaki Motoyama

Open access · goldAbstract read
In one paragraph

Article in Reproductive medicine and biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
5.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. The effect of laser-assisted hatching on clinical outcomes of frozen-thawed embryo transfer at different embryo ages.European journal of obstetrics & gynecology and reproductive biology: X · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Yuji EndoIVF Center Kurashiki Medical Clinic Kurashiki Japan.ORCID https://orcid.org/0000-0002-1861-5113
Shingo MitsuhataIVF Center Kurashiki Medical Clinic Kurashiki Japan.ORCID https://orcid.org/0000-0002-6954-0158
Momoko HayashiIVF Center Kurashiki Medical Clinic Kurashiki Japan.
Yoshitaka FujiiIVF Center Kurashiki Medical Clinic Kurashiki Japan.ORCID https://orcid.org/0000-0003-2207-4230
Hiroaki MotoyamaIVF Center Kurashiki Medical Clinic Kurashiki Japan.
Kurashiki Medical Center · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study determined the effect of laser-assisted hatching on the clinical and neonatal outcomes of single vitrified blastocyst transfer.

methodsFrom June 2014 to March 2018, 289 matched pairs after propensity score matching were analyzed. During the blastocyst warming procedure, a small section of the zona pellucida area in the empty perivitelline space was sliced off using multiple laser beams. The clinical and neonatal outcomes of the laser-treated group and non-treatment control were analyzed.

resultsIn the laser-assisted hatching group, significantly higher rates of clinical pregnancy (40.8% vs 29.4%,

conclusionsSingle vitrified blastocyst transfer treated with laser-assisted hatching increases the live birth rate and has no adverse effects on neonatal outcomes.

Indexed as

laser‐assisted hatchinglive birth rateneonatal outcomessingle vitrified blastocyst transfer

Identifiers

PMID33850451
PMCPMC8022098
OpenAlexW3125975259

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.