Evidence map›Paper›PMID 33850314›Full record

ArticleEuropean journal of clinical nutrition2022

Handgrip strength as a valid practical tool to screen early-onset sarcopenia in acute care wards: a first evaluation.

Marie Blanquet, Guillaume Ducher, Anaïs Sauvage, Sylvain Dadet, Vincent Guiyedi, Nicolas Farigon, Candy Guiguet-Auclair, Pauline Berland, Jérôme Bohatier, Yves Boirie and 1 more

Registry-linked trialAbstract read
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In one paragraph

Article in European journal of clinical nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07597850 (Effects of Traditional Chinese Medicine), which is not on this map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07597850 phase2recruitingnot on this mapstarted 2026, after this paper: background citation

Effects of Traditional Chinese Medicine (TCM) Formula vs. HMB on Muscle Strength and Bone Status in Pre-Frail Elders: A Comparative Study

TypeinterventionalSponsorTri-Service General Hospital (TSGH)Ran2026 to 2026Enrolled90ConditionsPre-Frailty, Sarcopenia, Muscle Atrophy or Weakness, OsteoporosisArmsTCM Formula, HMB (beta-Hydroxy-beta-methylbutyrate)
3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Association between reduced physical performance measures and short-term consequences after major emergency abdominal surgery: a prospective cohort study.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2024
    Observational
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Insulin-like growth factor 1 and dehydroepiandrosterone levels in alcoholic liver cirrhosis.JGH open : an open access journal of gastroenterology and hepatology · 2022
    Article
  10. Article
  11. Sarcopenia: if it looks/walks like a duck, it must be a duck.European journal of clinical nutrition · 2022
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Marie BlanquetService de Médecine, Centre Hospitalier de MAURIAC, Mauriac, France. mblanquet@chu-clermontferrand.fr.ORCID http://orcid.org/0000-0002-0062-2964
Guillaume DucherService de Gériatrie, BEAUMONT, Beaumont, France.ORCID http://orcid.org/0000-0001-8080-2457
Anaïs SauvageDiététicienne R&D-Chef de projet NutriSeniors. NUTRISET, Hameau du Bois Ricard - CS 80035 - 76770, MALAUNAY, France.
Sylvain DadetService de Médecine, Centre Hospitalier de BRIOUDE, Brioude, France.
Vincent GuiyediService de Médecine, Centre Hospitalier de MAURIAC, Mauriac, France.
Nicolas FarigonService de Nutrition Clinique, Centre Hospitalo-Universitaire de CLERMONT-FERRAND, Clermont-Ferrand, France.
Candy Guiguet-AuclairService de Santé Publique, Centre Hospitalo-Universitaire de CLERMONT-FERRAND, Clermont-Ferrand, France.ORCID http://orcid.org/0000-0002-0782-2889
Pauline BerlandService de Santé Publique, Centre Hospitalo-Universitaire de CLERMONT-FERRAND, Clermont-Ferrand, France.
Jérôme BohatierService de Gériatrie, Centre Hospitalier de Riom, RIOM, France.
Yves BoirieService de Nutrition Clinique, Centre Hospitalo-Universitaire de CLERMONT-FERRAND, Clermont-Ferrand, France.
Laurent GerbaudService de Santé Publique, Centre Hospitalo-Universitaire de CLERMONT-FERRAND, Clermont-Ferrand, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesSarcopenia is an age-related muscle disease associated with higher mortality, morbidity risk and health costs. An easy and convenient sarcopenia screening test would be hugely valuable for clinical critical care. The study aimed to assess handgrip strength (HGS) as a screening tool for sarcopenia in acute care-unit inpatients, using the EWGSOP 1 reference-standard definition. SUBJECTS/

methodsInpatients, aged 75 years old or above, of two acute care wards-a multidisciplinary care unit (MCU) and a geriatric care unit (GCU), were included between September 2017 and June 2018 in a cross-sectional study. HGS, sarcopenia, nutritional status, functional status, number of medications and sociodemographic data were collected. The accuracy of HGS as a screening test for sarcopenia was assessed by gender using receiver operating characteristic (ROC) curves and area under the curve (AUC) in a population of older patients (n = 223; age: 85.8 yrs; BMI: 26.7 kg/m²).

resultsScreening was positive (patients confirmed with sarcopenia by the HGS test) with cut-off values of 18 kg for women and 25.5 kg for men, with ROC analysis giving a sensitivity of 92.9% in women and 78.6% in men. ROC curve analysis found also that HGS should be strictly higher than 15 kg in women and 18 kg in men to maximise AUC. Prevalence of sarcopenia according to the EWGSOP1 definition was 31.8% (95% CI: 22.1-41.6%) in the MCU and 27.8% (95% CI: 19.6-36.0%) in the GCU.

conclusionsAcute care wards can use HGS as a valid, easy tool for early screening of sarcopenia.

Indexed as

SarcopeniaAgedAged, 80 and overCritical CareCross-Sectional StudiesFemaleHand StrengthHumansMaleMuscle StrengthPrevalence

Identifiers

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.