ArticleScientific reports2021
A comprehensive evaluation of early potential risk factors for disease aggravation in patients with COVID-19.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed, 10 citations in OpenAlex.
- The Hidden Pandemic of COVID-19-Induced Organizing Pneumonia.Pharmaceuticals (Basel, Switzerland) · 2022Review
- Protocol and clinical characteristics of patients under 'at-home care' for COVID-19 in South Korea: a retrospective cohort study.BMJ open · 2022Article
- Hallmarks of Severe COVID-19 Pathogenesis:Frontiers in immunology · 2022Review
- Correlates of COVID-19 Vaccine Hesitancy among a Community Sample of African Americans Living in the Southern United States.Vaccines · 2021Article
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Authors and funding
8 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The 2019 Coronavirus Disease (COVID-19) has become an unprecedented public crisis. We retrospectively investigated the clinical data of 197 COVID-19 patients and identified 88 patients as disease aggravation cases. Compared with patients without disease aggravation, the aggravation cases had more comorbidities, including hypertension (25.9%) and diabetes (20.8%), and presented with dyspnoea (23.4%), neutrophilia (31.5%), and lymphocytopenia (46.7%). These patients were more prone to develop organ damage in liver, kidney, and heart (P < 0.05). A multivariable regression analysis showed that advanced age, comorbidities, dyspnea, lymphopenia, and elevated levels of Fbg, CTnI, IL-6, and serum ferritin were significant predictors of disease aggravation. Further, we performed a Kaplan-Meier analysis to evaluate the prognosis of COVID-19 patients, which suggested that 64.9% of the patients had not experienced ICU transfers and survival from the hospital.
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