Evidence map›Paper›PMID 33849981›Full record

ArticlemBio2021

A Translation-Aborting Small Open Reading Frame in the Intergenic Region Promotes Translation of a Mg

Eunna Choi, Yoontak Han, Shinae Park, Hyojeong Koo, Jung-Shin Lee, Eun-Jin Lee

Open access · goldAbstract read
In one paragraph

Article in mBio, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Eunna ChoiDepartment of Life Sciences, School of Life Sciences and Biotechnology, Korea University, Seoul, South Korea.
Yoontak HanDepartment of Life Sciences, School of Life Sciences and Biotechnology, Korea University, Seoul, South Korea.
Shinae ParkDepartment of Molecular Bioscience, College of Biomedical Science, Kangwon National University, Chuncheon, South Korea.
Hyojeong KooDepartment of Molecular Bioscience, College of Biomedical Science, Kangwon National University, Chuncheon, South Korea.
Jung-Shin LeeDepartment of Molecular Bioscience, College of Biomedical Science, Kangwon National University, Chuncheon, South Korea.
Eun-Jin LeeDepartment of Life Sciences, School of Life Sciences and Biotechnology, Korea University, Seoul, South Korea eunjinlee@korea.ac.kr.ORCID 0000-0001-5078-1974
Kangwon National University · KRKorea University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacterial mRNAs often harbor upstream open reading frames (uORFs) in the 5' untranslated regions (UTRs). Translation of the uORF usually affects downstream gene expression at the levels of transcription and/or translation initiation. Unlike other uORFs mostly located in the 5' UTR, we discovered an 8-amino-acid ORF, designated

Indexed as

DNA, IntergenicOpen Reading FramesProtein Biosynthesis5' Untranslated RegionsCation Transport ProteinsGene Expression Regulation, BacterialMagnesiumOperonSalmonella typhimuriumVirulenceVirulence Factors5' Untranslated RegionsCation Transport ProteinsDNA, IntergenicMagnesiumVirulence Factorsintergenic regionribosome destabilizationtranslation-inhibitory stem-loop structureuORF

Identifiers

PMID33849981
PMCPMC8092293
OpenAlexW3154797631

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.