Evidence map›Paper›PMID 33849966›Full record

ArticleCancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology2021

Food Insecurity Is an Independent Risk Factor for Depressive Symptoms in Survivors of Digestive Cancers.

Katelyn E Madigan, David A Leiman, Deepak Palakshappa

Open access · bronzeAbstract read
In one paragraph

Article in Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Food assistance strategies for patients of an infusion clinic: a pilot randomized controlled trial (protocol number: STU-2023-0387).Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Trial
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  6. Patient-reported benefit from proposed interventions to reduce financial toxicity during cancer treatment.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Katelyn E MadiganDepartment of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina.ORCID 0000-0002-7484-7816
David A LeimanDivision of Gastroenterology, Duke University School of Medicine, Durham, North Carolina.ORCID 0000-0001-6350-3906
Deepak PalakshappaDepartment of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina. dpalaksh@wakehealth.edu.ORCID 0000-0003-1467-4965
Wake Forest University · USDuke University · US

Funding

Mobile Technology for Primary Care to Address Food Insecurity and Improve Cardiovascular HealthK23HL146902 · NHLBI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI PALAKSHAPPA, DEEPAK · 2020 to 2024
$776k
NHLBI NIH HHS K23 HL146902
6 · The paper itself

Abstract

backgroundColorectal and other digestive cancer survivors are at increased risk of depression, which can negatively affect health outcomes. Food insecurity (FI), the lack of consistent access to enough food, can also contribute to these health complications. The objective of this study was to determine the relationship between FI and depressive symptoms within this population.

methodsWe conducted a cross-sectional analysis of data from the 2007-2016 National Health and Nutrition Examination Survey. We included all adults (≥20 years) with a self-reported history of a digestive cancer (including colorectal, esophageal, stomach, liver, and pancreas cancer). Our primary exposure was household FI, and our outcome of interest was depressive symptoms, as measured by the validated 9-item Patient Health Questionnaire. We used multivariable ordinal logistic regression to test the association between FI and depressive symptoms, controlling for demographic and clinical covariates.

resultsWe included 229 adult digestive cancer survivors (weighted

conclusionsAmong a nationally representative sample of colorectal cancer and other digestive cancer survivors, FI was associated with increased odds of depressive symptoms. IMPACT: This study adds further evidence to the negative impact FI may have on survivors' physical and mental health.

Indexed as

Food InsecurityAdultCancer SurvivorsCross-Sectional StudiesDepressionDigestive System NeoplasmsFemaleHumansMaleMiddle AgedNutrition SurveysPatient Health QuestionnaireRisk FactorsSelf ReportSeverity of Illness IndexUnited States

Identifiers

PMID33849966
PMCPMC8172480
OpenAlexW3152708104

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.