Evidence map›Paper›PMID 33849909›Full record

ArticleBritish journal of sports medicine2021

Physical inactivity is associated with a higher risk for severe COVID-19 outcomes: a study in 48 440 adult patients.

Robert Sallis, Deborah Rohm Young, Sara Y Tartof, James F Sallis, Jeevan Sall, Qiaowu Li, Gary N Smith, Deborah A Cohen

Registry-linked trialAbstract read
PubMed Publisher
In one paragraph

Article in British journal of sports medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07046442 (Effect of Pulmonary Rehabilitation and Physical Activity on the Symptoms of Long COVID. A Pilot Study), which is not on this map. Cited by 360 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
360citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07046442 completednot on this mapstarted 2022, after this paper: background citation

Effect of Pulmonary Rehabilitation and Physical Activity on the Symptoms of Long COVID. A Pilot Study

Typeobservational_patient_registrySponsorUniversity of ParmaRan2022 to 2025Enrolled40ConditionsCOVID - 19ArmsPulmonary Rehabilitation
3 · Its place in the literature

Who cites it

360 citing papers in PubMed, 6 syntheses or guidelines pooled it.

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  4. Physical activity promotion interventions in chronic airways disease: a systematic review and meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2023
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300 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Robert SallisDepartment of Family and Sports Medicine, Kaiser Permanente Medical Center, Fontana, California, USA Robert.E.Sallis@kp.org.ORCID http://orcid.org/0000-0001-7633-7345
Deborah Rohm YoungResearch and Evaluation, Southern California Permanente Medical Group, Pasadena, California, USA.
Sara Y TartofResearch and Evaluation, Southern California Permanente Medical Group, Pasadena, California, USA.
James F SallisUniversity of California San Diego, La Jolla, California, USA.
Jeevan SallDepartment of Family and Sports Medicine, Kaiser Permanente Medical Center, Fontana, California, USA.
Qiaowu LiResearch and Evaluation, Southern California Permanente Medical Group, Pasadena, California, USA.
Gary N SmithEconomics Department, Pomona College, Claremont, California, USA.
Deborah A CohenResearch and Evaluation, Southern California Permanente Medical Group, Pasadena, California, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo compare hospitalisation rates, intensive care unit (ICU) admissions and mortality for patients with COVID-19 who were consistently inactive, doing some activity or consistently meeting physical activity guidelines.

methodsWe identified 48 440 adult patients with a COVID-19 diagnosis from 1 January 2020 to 21 October 2020, with at least three exercise vital sign measurements from 19 March 2018 to 18 March 2020. We linked each patient's self-reported physical activity category (consistently inactive=0-10 min/week, some activity=11-149 min/week, consistently meeting guidelines=150+ min/week) to the risk of hospitalisation, ICU admission and death after COVID-19 diagnosis. We conducted multivariable logistic regression controlling for demographics and known risk factors to assess whether inactivity was associated with COVID-19 outcomes.

resultsPatients with COVID-19 who were consistently inactive had a greater risk of hospitalisation (OR 2.26; 95% CI 1.81 to 2.83), admission to the ICU (OR 1.73; 95% CI 1.18 to 2.55) and death (OR 2.49; 95% CI 1.33 to 4.67) due to COVID-19 than patients who were consistently meeting physical activity guidelines. Patients who were consistently inactive also had a greater risk of hospitalisation (OR 1.20; 95% CI 1.10 to 1.32), admission to the ICU (OR 1.10; 95% CI 0.93 to 1.29) and death (OR 1.32; 95% CI 1.09 to 1.60) due to COVID-19 than patients who were doing some physical activity.

conclusionsConsistently meeting physical activity guidelines was strongly associated with a reduced risk for severe COVID-19 outcomes among infected adults. We recommend efforts to promote physical activity be prioritised by public health agencies and incorporated into routine medical care.

Indexed as

Intensive Care UnitsSedentary BehaviorAdultAgedAged, 80 and overCOVID-19FemaleHospitalizationHumansMaleMiddle AgedSARS-CoV-2COVID-19exercisephysical activity

Identifiers

PMID33849909

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.