Evidence map›Paper›PMID 33849860›Full record

ArticleBMJ open2021

Patient outcomes and costs associated with functional medicine-based care in a shared versus individual setting for patients with chronic conditions: a retrospective cohort study.

Michelle Beidelschies, Marilyn Alejandro-Rodriguez, Ning Guo, Anna Postan, Tawny Jones, Elizabeth Bradley, Mark Hyman, Michael B Rothberg

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

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  6. Functional MedicineIntegrative medicine (Encinitas, Calif.) · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Michelle BeidelschiesCenter for Functional Medicine, Cleveland Clinic, Cleveland, Ohio, USA beidelm2@ccf.org.ORCID 0000-0002-6344-0674
Marilyn Alejandro-RodriguezCommunity Health and Partnerships, Cleveland Clinic, Cleveland, Ohio, USA.
Ning GuoQuantitative Health Sciences, Cleveland Clinic, Cleveland, Ohio, USA.
Anna PostanCommunity Care, Cleveland Clinic, Cleveland, Ohio, USA.
Tawny JonesCenter for Functional Medicine, Cleveland Clinic, Cleveland, Ohio, USA.
Elizabeth BradleyCenter for Functional Medicine, Cleveland Clinic, Cleveland, Ohio, USA.
Mark HymanCenter for Functional Medicine, Cleveland Clinic, Cleveland, Ohio, USA.
Michael B RothbergInternal Medicine, Cleveland Clinic, Cleveland, Ohio, USA.
Cleveland Clinic · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo compare outcomes and costs associated with functional medicine-based care delivered in a shared medical appointment (SMA) to those delivered through individual appointments.

designA retrospective cohort study was performed to assess outcomes and cost to deliver care to patients in SMAs and compared with Propensity Score (PS)-matched patients in individual appointments.

settingA single-centre study performed at Cleveland Clinic Center for Functional Medicine.

participantsA total of 9778 patients were assessed for eligibility and 7323 excluded. The sample included 2455 patients (226 SMAs and 2229 individual appointments) aged ≥18 years who participated in in-person SMAs or individual appointments between 1 March 2017 and 31 December 2019. Patients had a baseline Patient-Reported Outcome Measurement Information System (PROMIS) Global Physical Health (GPH) score and follow-up score at 3 months. Patients were PS-matched 1:1 with 213 per group based on age, sex, race, marital status, income, weight, body mass index, blood pressure (BP), PROMIS score and functional medicine diagnostic category. PRIMARY AND SECONDARY OUTCOME MEASURES: The primary outcome was change in PROMIS GPH at 3 months. Secondary outcomes included change in PROMIS Global Mental Health (GMH), biometrics, and cost.

resultsAmong 213 PS-matched pairs, patients in SMAs exhibited greater improvements at 3 months in PROMIS GPH T-scores (mean difference 1.18 (95% CI 0.14 to 2.22), p=0.03) and PROMIS GMH T-scores (mean difference 1.78 (95% CI 0.66 to 2.89), p=0.002) than patients in individual appointments. SMA patients also experienced greater weight loss (kg) than patients in individual appointments (mean difference -1.4 (95% CI -2.15 to -0.64), p<0.001). Both groups experienced a 5.5 mm Hg improvement in systolic BP. SMAs were also less costly to deliver than individual appointments.

conclusionSMAs deliver functional medicine-based care that improves outcomes more than care delivered in individual appointments and is less costly to deliver.

Indexed as

Appointments and SchedulesPatient Reported Outcome MeasuresAdolescentAdultHumansIncomePatient CareRetrospective Studiescomplementary medicinenutrition & dieteticspreventive medicinequality in health care

Identifiers

PMID33849860
PMCPMC8051390
OpenAlexW3154253720

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.