ArticleChinese medicine2021
The influence of TCM constitutions and neurocognitive function in elderly Macau individuals.
Article in Chinese medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Efficacy and Safety of Shenfu Injection for Severe Pneumonia in the Elderly: A Systematic Review and Meta-Analysis Based on Western and Eastern Medicine.Frontiers in pharmacology · 2022Pooled it
- Association between Traditional Chinese Medicine constitution and geriatric functional impairment evaluated by the integrated care for older people approach in the elderly.Journal of traditional and complementary medicine · 2026Article
- A Machine Learning and Traditional Chinese Medicine Constitution-Based Prediction Model for Mild Cognitive Impairment in Community-Dwelling Older Adults.Neuropsychiatric disease and treatment · 2026Article
- Advances in brain MRI for CAD-associated cognitive impairment with supplementary perspectives from traditional Chinese medicine.Frontiers in medicine · 2026Review
- Identification of characteristic genes ofanddeficiency constitutions: an integrated analysis based on bioinformatics and machine learning.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan · 2025Article
- Article
- Traditional Chinese Medicine Constitution and Cognitive Frailty in Older Adults: Prediction Models and Sleep-Quality Mediation Pathway from a Multicenter Study in China.Clinical interventions in aging · 2025Article
- The original scores of traditional Chinese medicine constitutions are risk and diagnostic factors in middle-aged and older adults with sarcopenia.Aging medicine (Milton (N.S.W)) · 2024Article
- A comprehensive study of psychological well-being and traditional Chinese medicine constitutions among model workers in Beijing.Frontiers in psychiatry · 2024Article
- Traditional Chinese medicine constitution and sarcopenia: a cross-sectional study.Frontiers in public health · 2024Article
- A multi-omics analysis for the prediction of neurocognitive disorders risk among the elderly in Macao.Clinical and translational medicine · 2022Article
- Relationships Between Traditional Chinese Medicine Constitution and Age-Related Cognitive Decline in Chinese Centenarians.Frontiers in aging neuroscience · 2022Article
- A Role of Socioeconomic Status in Cognitive Impairment Among Older Adults in Macau: A Decomposition Approach.Frontiers in aging neuroscience · 2022Article
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7 authors.
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Abstract
backgroundTraditional Chinese medicine (TCM) constitution contributes to predicating disease occurrence and pathological progress. In this study, we investigate the correlation between TCM constitution and neurocognitive function in elderly Macau individuals.
methodsA total of 313 older adults from elderly healthcare centers were recruited at random. The data of gender, age, education, sleeping hours, physical activities were collected, and the Geriatric Depression Scale, Hong Kong version of the Montreal Cognitive Assessment (MoCA) and categories of TCM constitution were administered.
resultsOf the 313 elderly individuals enrolled in this study, 86 (27.48%) were of balanced constitution. Among the other categories of TCM constitution, the most was Yin-deficiency (23.32%), followed by 53 (16.93%) with Phlegm-dampness. The average neurocognitive score of all elderly individuals was 18.01 ± 6.25. After adjusting for all possible confounds, multiple linear regression analysis showed that Qi-depressed constitution and neurocognitive scores were negatively correlated (β = - 2.66, 95%CI - 4.99 ~ - 0.33), Meanwhile, Yin-deficient constitution and neurocognitive scores were negatively correlated (β = - 2.10, 95%CI - 3.73 ~ - 0.47). Compared with balanced constitution, Qi-depressed constitution mainly affected visual-spatial ability dimension (β = - 0.91, 95%CI - 1.54 ~ - 0.28) and naming dimension (β = - 0.64, 95%CI - 1.04 ~ - 0.25), Yin-deficient constitution mainly affected visual space dimension (β = - 0.53, 95%CI - 0.97 ~ - 0.08).
conclusionQi-depressed and Yin-deficient constitutions are associated with and contributed to the decline of neurocognitive function in senior adults, especially visual-spatial ability and naming dimensions. Further investigations into how TCM constitutions interact with neurocognitive function are needed.
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