ArticleJournal of orthopaedic surgery and research2021
Histological analysis of induced membranes in patients whose bone defects were treated with the Masquelet technique to identify factors affecting the vascularity of induced membranes.
Article in Journal of orthopaedic surgery and research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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9 citing papers in PubMed, 12 citations in OpenAlex.
- [A prospective randomized controlled study of antibiotic bone cement in the treatment of diabetic foot ulcer].Zhonghua shao shang yu chuang mian xiu fu za zhi · 2023Trial
- Management of a Symphyseal Multilocular Odontogenic Keratocyst.Journal of medical cases · 2026Article
- Clinical Observations of the Effectiveness of the Masquelet Induced Membrane Technique in the Treatment of Critical Long-Bone Defects of the Lower and Upper Extremities.Medicina (Kaunas, Lithuania) · 2024Article
- Discovery of multipotent progenitor cells from human induced membrane: Equivalent to periosteum-derived stem cells in bone regeneration.Journal of orthopaedic translation · 2023Article
- Restoring the Anatomy of Long Bones with Large Septic Non-Union Defects with the Masquelet Technique.Maedica · 2023Article
- Management of wounds with exposed bone structures using an induced-membrane followed by polymethyl methacrylate and second-stage skin grafting in the elderly with a 3-year follow-up.International wound journal · 2023Article
- Masquelet technique combined with modified Sauve‑Kapandji, negative pressure drainage and flap transplantation for the treatment of a Gustilo‑Anderson III type C open fracture of the forearm: A case report.Experimental and therapeutic medicine · 2022Article
- Immunohistochemical analysis revealed the expression of bone morphogenetic proteins-4, 6, 7, and 9 in human induced membrane samples treated with the Masquelet technique.Journal of orthopaedic surgery and research · 2022Article
- The Masquelet Technique: Is Bone Regeneration Influenced by Biological Sex?Strategies in trauma and limb reconstructionArticle
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Authors and funding
11 authors at 1 institution in 1 country.
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Abstract
backgroundRich vascularity of the induced membrane (IM) is important for Masquelet reconstruction surgery. The factors affecting IM vascularity are not completely understood. This study aimed to investigate these factors using histological samples of human IMs.
methodsWe retrospectively evaluated 36 patients whose bone defects were treated using the Masquelet technique. Two clinical pathologists analyzed histological sections of IM pieces (1 cm
resultsIM formation with rich vascularity and some inflammation, foreign body reaction, and fibrosis were histologically confirmed in all patients. We found 37.4 ± 19.1 blood vessels per 1 mm
conclusionSex, patient age, smoking, diabetes mellitus, femur or tibia, duration of cement spacer placement, and antibiotic impregnation to the cement did not affect IM vascularization. IM vascularization was reduced in patients with than in those without free flap surgery.
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