ArticleJournal of orthopaedic surgery and research2021
Elderly patients with concurrent hip fracture and lower respiratory tract infection: the pathogens and prognosis over different bedridden periods.
Article in Journal of orthopaedic surgery and research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 19 citations in OpenAlex.
- Copper-rhein nanozymes induce bacterial activation-exhaustion death for the treatment of bacterial pneumonia and infected wounds.Journal of nanobiotechnology · 2026Article
- Effect of sarcopenia combined with Metabolic Syndrome (MS) on the prognosis of intertrochanteric fractures: a retrospective clinical study.BMC musculoskeletal disorders · 2025Article
- Critical Management of Septic Orthopedic Patients: The Impact of Intensive Care on Survival and Recovery.Life (Basel, Switzerland) · 2025Article
- Examination of factors causing postoperative pneumonia in elderly hip fracture patients: A narrative review.Medicine · 2025Review
- Development and validation of a nomogram for predicting in-hospital mortality in older adult hip fracture patients with atrial fibrillation: a retrospective study.Frontiers in medicine · 2025Article
- Infection with multi‑drug resistant organisms in patients with limb fractures: Analysis of risk factors and pathogens.Biomedical reports · 2024Article
- Article
- Random forest predictive modeling of prolonged hospital length of stay in elderly hip fracture patients.Frontiers in medicine · 2024Article
- Risk factors for short-term mortality in elderly hip fracture patients with complicated heart failure in the ICU: A MIMIC-IV database analysis using nomogram.Journal of orthopaedic surgery and research · 2023Article
- Determination of risk factors of postoperative pneumonia in elderly patients with hip fracture: What can we do?PloS one · 2022Article
- Relationship Between Invasive Fungal Infection and Hypostatic Pneumonia: A Prospective Cohort Study.Frontiers in microbiology · 2022Article
- The pulmonary infection risk factors in long-term bedridden patients: a meta-analysis.American journal of translational research · 2021Article
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundElderly patients who experience hip fractures often become bedridden and are at risk of developing lower respiratory tract infections. The current study was to investigate the etiology and bacterial drug resistance patterns of elderly patients with hip fractures and lower respiratory tract infections on prolonged bedridden time and to determine their prognosis.
methodsPatients diagnosed with hip fractures admitted from May 2015 to April 2017 were included. The basic characteristics including the patients' gender, age, fracture type, operation mode, bedridden duration, length of hospital stay, prognosis, past medical history, routine bloodwork, C-reactive protein (CRP), procalcitonin (PCT), blood biochemistry, blood gas analysis, glycosylated hemoglobin (HbA1C%), sputum smear, sputum culture, and anti-infection and related therapy were recorded. All patients were classified into three groups based on bed rest duration, including short-term (<1 month), mid-term (1-12 months), and long-term (> 12 months). The correlation between the bedridden time and the patients' basic characteristics, disease history, laboratory examination results, pathogen, anti-infection, and related therapy were evaluated. The risk factors related to the prognosis of the disease were investigated.
resultsProlonged bed rest in patients led to an increase in hospitalization time, mortality rates, and decreased serum albumin levels (P < 0.05). Sputum bacteriological culture results showed that, with bed rest prolongation, the proportion of Pseudomonas aeruginosa and fungal infections increased. Binomial logistic regression of pulmonary infection prognosis, glucocorticoid use during the anti-infective period, prolonged bedridden time, and serum albumin level showed that intravenous use of glucocorticoid during anti-infective treatment, bed rest > 1 year, and low serum albumin level were related to poor prognosis.
conclusionElderly hip fracture patients with prolonged bedridden time had an increased chance of opportunistic pulmonary infection and decreased nutritional status. Glucocorticoids should be used cautiously.
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