Evidence map›Paper›PMID 33849254›Full record

ArticleJournal of public health research2021

Dynamic estimation of epidemiological parameters of COVID-19 outbreak and effects of interventions on its spread.

Hongzhe Zhang, Xiaohang Zhao, Kexin Yin, Yiren Yan, Wei Qian, Bintong Chen, Xiao Fang

Open access · goldAbstract read
In one paragraph

Article in Journal of public health research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 64% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Hongzhe ZhangInstitute for Financial Services Analytics, University of Delaware, Newark, DE. hzhang@udel.edu.
Xiaohang ZhaoInstitute for Financial Services Analytics, University of Delaware, Newark, DE. xhfsan@udel.edu.
Kexin YinInstitute for Financial Services Analytics, University of Delaware, Newark, DE. yinkexin@udel.edu.
Yiren YanInstitute for Financial Services Analytics, University of Delaware, Newark, DE. yanyiren@udel.edu.
Wei QianInstitute for Financial Services Analytics, and Department of Applied Economics and Statistics, University of Delaware, Newark, DE. weiqian@udel.edu.
Bintong ChenInstitute for Financial Services Analytics Lerner College of Business and Economics, University of Delaware, Newark, DE. bchen@udel.edu.
Xiao FangInstitute for Financial Services Analytics Lerner College of Business and Economics, University of Delaware, Newark, DE. xfang@udel.edu.
University of Delaware · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA key challenge in estimating epidemiological parameters for a pandemic such as the initial COVID-19 outbreak in Wuhan is the discrepancy between the officially reported number of infections and the true number of infections. A common approach to tackling the challenge is to use the number of infections exported from the originating city to infer the true number. This approach can only provide a static estimate of the epidemiological parameters before city lockdown because there are almost no exported cases thereafter.

methodsWe propose a Bayesian estimation method that dynamically estimates the epidemiological parameters by recovering true numbers of infections from day-to-day official numbers. To illustrate the use of this method, we provide a comprehensive retrospection on how the COVID-19 had progressed in Wuhan from January 19 to March 5, 2020. Particularly, we estimate that the outbreak sizes by January 23 and March 5 were 11,239 [95% CI 4,794-22,372] and 124,506 [95% CI 69,526-265,113], respectively.

resultsThe effective reproduction number attained its maximum on January 24 (3.42 [95% CI 3.34-3.50]) and became less than 1 from February 7 (0.76 [95% CI 0.65-0.92]). We also estimate the effects of two major government interventions on the spread of COVID-19 in Wuhan.

conclusionsThis case study by our proposed method affirms the believed importance and effectiveness of imposing tight non-essential travel restrictions and affirm the importance and effectiveness of government interventions (e.g., transportation suspension and large scale hospitalization) for effective mitigation of COVID-19 community spread.

Identifiers

PMID33849254
PMCPMC7967497
OpenAlexW3134427134

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.