ArticleJournal of clinical microbiology1988
Influence of strain characteristics and immunity on the epidemiology of Campylobacter infections in Thailand.
Article in Journal of clinical microbiology, 1988. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it, 100 citations in OpenAlex.
- Intensified food production and correlated risks to human health in the Greater Mekong Subregion: a systematic review.Environmental health : a global access science source · 2015Pooled it
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- Distribution of genes related to Type 6 secretion system and lipooligosaccharide that induced ganglioside mimicry amongGut pathogens · 2020Article
- Modelling the transmission dynamics ofRoyal Society open science · 2019Article
- Climate, human behaviour or environment: individual-based modelling of Campylobacter seasonality and strategies to reduce disease burden.Journal of translational medicine · 2019Article
- Incidence ofGut pathogens · 2017Article
- Epidemiology and RAPD-PCR typing of thermophilic campylobacters from children under five years and chickens in Morogoro Municipality, Tanzania.BMC infectious diseases · 2016Article
- Campylobacter infections in children exposed to infected backyard poultry in Egypt.Epidemiology and infection · 2015Article
- Article
- The burden of different pathogens in acute diarrhoeal episodes among a cohort of Egyptian children less than five years old.Przeglad gastroenterologiczny · 2015Article
- Campylobacter infection in a cohort of rural children in Moramanga, Madagascar.BMC infectious diseases · 2014Article
- A capsule conjugate vaccine approach to prevent diarrheal disease caused by Campylobacter jejuni.Human vaccines & immunotherapeutics · 2014Review
- Serologic host response to Helicobacter pylori and Campylobacter jejuni in socially housed Rhesus macaques (Macaca mulatta).Gut pathogens · 2012Article
- PFGE, Lior serotype, and antimicrobial resistance patterns among Campylobacter jejuni isolated from travelers and US military personnel with acute diarrhea in Thailand, 1998-2003.Gut pathogens · 2010Article
- Assessment of the duration of protection in Campylobacter jejuni experimental infection in humans.Infection and immunity · 2010Article
- Campylobacter immunity and coinfection following a large outbreak in a farming community.Journal of clinical microbiology · 2009Article
- Novel insight in the association between salmonellosis or campylobacteriosis and chronic illness, and the role of host genetics in susceptibility to these diseases.Epidemiology and infection · 2008Article
- Host-pathogen interactions in Campylobacter infections: the host perspective.Clinical microbiology reviews · 2008Review
- New World monkey Aotus nancymae as a model for Campylobacter jejuni infection and immunity.Infection and immunity · 2006Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To determine how strain differences and immunity affect the clinical expression of Campylobacter infections, we conducted a study of acute diarrheal disease in Thailand in which specimens from children with Campylobacter infections were cultured weekly for up to 12 weeks to determine the serotype-specific length of time of convalescent-phase excretion and rate of reinfection. Levels of immunoglobulin G to cell-surface antigens of C. jejuni were determined in another population of healthy children who were closely related by age and location to the children in the diarrheal disease study. Campylobacter species were initially isolated from 18% of 586 children under 5 years old with diarrhea; most isolates in Thailand belonged to serotypes commonly found in developed countries. C. coli was significantly less often associated with symptomatic infections and with bloody diarrhea than C. jejuni (P less than 0.001 and P = 0.045, respectively). The peak age of isolation and the peak level of immunoglobulin G to Campylobacter species occurred before 2 years of age. The mean duration of convalescent-phase excretion was 14 +/- 2 (standard error of the mean) days for children less than 1 year old and 8 +/- 2 days for children 1 to 5 years old (P = 0.02, t test). Infection with another Campylobacter serotype was found in 34% of 105 children during the 12-week follow-up period. The rate of reinfection in these children was 15% (range, 8 to 22%) each week. Hyperendemic exposure to Campylobacter species in Thailand confers immunity to infection that is associated with an early peak in specific serum antibodies and an age-related decrease in the case-to-infection ratio and duration of convalescent-phase excretion but does not prevent asymptomatic infections.
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