Evidence map›Paper›PMID 33849075›Full record

ArticleNucleic acids research2021

iNetModels 2.0: an interactive visualization and database of multi-omics data.

Muhammad Arif, Cheng Zhang, Xiangyu Li, Cem Güngör, Buğra Çakmak, Metin Arslantürk, Abdellah Tebani, Berkay Özcan, Oğuzhan Subaş, Wenyu Zhou and 9 more

Abstract read
In one paragraph

Article in Nucleic acids research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Trial
  4. Article
  5. Review
  6. Article
  7. Longitudinal big biological data in the AI era.Molecular systems biology · 2025
    Review
  8. Article
  9. Article
  10. Genome-scale models in human metabologenomics.Nature reviews. Genetics · 2025
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Muhammad ArifScience for Life Laboratory, KTH - Royal Institute of Technology, Stockholm SE-171 21, Sweden.
Cheng ZhangScience for Life Laboratory, KTH - Royal Institute of Technology, Stockholm SE-171 21, Sweden.ORCID 0000-0002-3721-8586
Xiangyu LiScience for Life Laboratory, KTH - Royal Institute of Technology, Stockholm SE-171 21, Sweden.
Cem GüngörBash Biotech Inc, 600 West Broadway, Suite 700, San Diego, CA, USA.
Buğra ÇakmakBash Biotech Inc, 600 West Broadway, Suite 700, San Diego, CA, USA.
Metin ArslantürkBash Biotech Inc, 600 West Broadway, Suite 700, San Diego, CA, USA.
Abdellah TebaniDepartment of Metabolic Biochemistry, Rouen University Hospital, 76000 Rouen, France.
Berkay ÖzcanBash Biotech Inc, 600 West Broadway, Suite 700, San Diego, CA, USA.
Oğuzhan SubaşBash Biotech Inc, 600 West Broadway, Suite 700, San Diego, CA, USA.
Wenyu ZhouDepartment of Genetics, Stanford University, Stanford, CA 94305, USA.
Brian PieningProvidence Cancer Center, Oregon Area, Portland, OR, USA.
Hasan TurkezDepartment of Medical Biology, Faculty of Medicine, Atatürk University, Erzurum, Turkey.
Linn FagerbergScience for Life Laboratory, KTH - Royal Institute of Technology, Stockholm SE-171 21, Sweden.
Nathan PriceInstitute of Systems Biology, Seattle, USA.
Leroy HoodInstitute of Systems Biology, Seattle, USA.
Michael SnyderDepartment of Genetics, Stanford University, Stanford, CA 94305, USA.
Jens NielsenDepartment of Biology and Biological Engineering, Chalmers University of Technology, Gothenburg, Sweden.ORCID 0000-0002-9955-6003
Mathias UhlenScience for Life Laboratory, KTH - Royal Institute of Technology, Stockholm SE-171 21, Sweden.
Adil MardinogluScience for Life Laboratory, KTH - Royal Institute of Technology, Stockholm SE-171 21, Sweden.ORCID 0000-0002-4254-6090

Funding

Quantitative Systems BiologyP50GM076547 · NIGMS · INSTITUTE FOR SYSTEMS BIOLOGY · PI BALIGA, NITIN S · 2006 to 2016
$30.6M
Strategic Vision & Impact on Environmental HealthP30ES017885 · NIEHS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Dana Dolinoy · 2011 to 2026
$21.3M
Complete Human Peptide- and MRM-AtlasRC2HG005805 · NHGRI · INSTITUTE FOR SYSTEMS BIOLOGY · PI HOOD, LEROY E, MORITZ, ROBERT L · 2009 to 2010
$4.6M
NHGRI NIH HHS RC2 HG005805NIEHS NIH HHS P30 ES017885NIGMS NIH HHS P50 GM076547
6 · The paper itself

Abstract

It is essential to reveal the associations between various omics data for a comprehensive understanding of the altered biological process in human wellness and disease. To date, very few studies have focused on collecting and exhibiting multi-omics associations in a single database. Here, we present iNetModels, an interactive database and visualization platform of Multi-Omics Biological Networks (MOBNs). This platform describes the associations between the clinical chemistry, anthropometric parameters, plasma proteomics, plasma metabolomics, as well as metagenomics for oral and gut microbiome obtained from the same individuals. Moreover, iNetModels includes tissue- and cancer-specific Gene Co-expression Networks (GCNs) for exploring the connections between the specific genes. This platform allows the user to interactively explore a single feature's association with other omics data and customize its particular context (e.g. male/female specific). The users can also register their data for sharing and visualization of the MOBNs and GCNs. Moreover, iNetModels allows users who do not have a bioinformatics background to facilitate human wellness and disease research. iNetModels can be accessed freely at https://inetmodels.com without any limitation.

Indexed as

Databases, FactualGastrointestinal MicrobiomeMetabolomicsMetagenomicsProteomicsAgedAged, 80 and overGene Regulatory NetworksHumansMiddle AgedMouthNeoplasmsNon-alcoholic Fatty Liver DiseaseSoftware

Identifiers

PMID33849075
PMCPMC8262747

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.