Evidence map›Paper›PMID 33848417›Full record

ArticleClinical and experimental pediatrics2021

Efficacy of probiotics for managing infantile colic due to their anti-inflammatory properties: a meta-analysis and systematic review.

Reza Shirazinia, Ali Akbar Golabchifar, Mohammad Reza Fazeli

2 registry-linked trialsOpen access · diamondAbstract read
In one paragraph

Article in Clinical and experimental pediatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06197100 naunknown statusnot on this mapstarted 2024, after this paper: background citation

Effectiveness of Supportive Care Training Given to Mothers of Babies With Infant Colic: Randomized Controlled Study

TypeinterventionalSponsorKirsehir Ahi Evran UniversitesiRan2024 to 2024Enrolled60ConditionsMothers, Infantile ColicArmsSupportive care training, control grups
NCT06299358 naunknown statusnot on this mapstarted 2023, after this paper: background citation

The Effect of Foot Massage and Maternal Heart Sound on Colic and Comfort Levels in Infants With Infantile Colic

TypeinterventionalSponsorKaramanoğlu Mehmetbey UniversityRan2023 to 2025Enrolled90ConditionsNurse's Role, Infantile ColicArmsFoot massage, Mother heart sound, Foot massage and maternal heart sound
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Infantile Colic and the Subsequent Development of the Irritable Bowel Syndrome.Journal of neurogastroenterology and motility · 2022
    Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Reza ShiraziniaDepartment of Comparative Biosciences, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran.
Ali Akbar GolabchifarDepartment of Comparative Biosciences, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran.
Mohammad Reza FazeliPharmaceutical Quality Assurance Research Center, The institute of Pharmaceutical Sciences (TIPS), Tehran University of Medical Sciences, Tehran, Iran.
University of Tehran · IRTehran University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInfantile colic (IC) is excessive crying in otherwise healthy children. Despite vast research efforts, its etiology remains unknown. PURPOSE: Most treatments for IC carry various side effects. The collection of evidence may inform researchers of new strategies for the management and treatment of IC as well as new clues for understanding its pathogenesis. This review and meta-analysis aimed to evaluate the efficacy and possible mechanisms of probiotics for mananaging IC.

methodsTen papers met the study inclusion and exclusion criteria, and the meta-analysis was conducted using Review Manager (RevMan) software and a random-effects model.

resultsThis meta-analysis revealed that probiotics are effective for treating infantile colic, while the review showed that this efficacy may be due to their anti-inflammatory effects.

conclusionProbiotics may be an important treatment option for managing infantile colic due to their anti-inflammatory properties.

Indexed as

CytokinesGastrointestinal inflammationInfantile colicMeta-analysisProbiotics

Identifiers

PMID33848417
PMCPMC8650819
OpenAlexW3155518249

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.