Evidence map›Paper›PMID 33847972›Full record

ArticleJournal of ultrasound2022

Point-of-care lung and diaphragm ultrasound in a patient with spinal muscular atrophy with respiratory distress type 1.

Beatrice Berti, Danilo Buonsenso, Cristina De Rose, Gloria Ferrantini, Roberto De Sanctis, Nicola Forcina, Eugenio Mercuri, Marika Pane

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of ultrasound, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Exploring the relationship betweenFrontiers in neuroscience · 2023
    Pooled it
  2. Article
  3. Observational
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Beatrice Berti *Paediatric Neurology Unit and Centro Clinico Nemo, Department of Woman and Child Health and Public Health, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy.
Danilo Buonsenso *Department of Woman and Child Health and Public Health, Fondazione Policlinico Universitario A. Gemelli IRCCS, Largo Agostino Gemelli 8, 00168, Roma, Italy. danilobuonsenso@gmail.com.ORCID http://orcid.org/0000-0001-8567-2639
Cristina De RoseDepartment of Woman and Child Health and Public Health, Fondazione Policlinico Universitario A. Gemelli IRCCS, Largo Agostino Gemelli 8, 00168, Roma, Italy.
Gloria FerrantiniPaediatric Neurology Unit and Centro Clinico Nemo, Department of Woman and Child Health and Public Health, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy.
Roberto De SanctisPaediatric Neurology Unit and Centro Clinico Nemo, Department of Woman and Child Health and Public Health, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy.
Nicola ForcinaPaediatric Neurology Unit and Centro Clinico Nemo, Department of Woman and Child Health and Public Health, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy.
Eugenio MercuriPaediatric Neurology Unit and Centro Clinico Nemo, Department of Woman and Child Health and Public Health, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy.
Marika PanePaediatric Neurology Unit and Centro Clinico Nemo, Department of Woman and Child Health and Public Health, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy.
Centro Clinico Nemo · ITUniversità Cattolica del Sacro Cuore · ITAgostino Gemelli University Polyclinic · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Spinal muscular atrophy with respiratory distress type 1 (SMARD1, OMIM #604,320), is a rare autosomal recessive disease resulting from degeneration of motor neurons in the anterior horns, which leads irreversible diaphragmatic palsy and progressive distal symmetrical muscular weakness. Respiratory distress is the main symptom and is severe, rapidly progressive, and frequently requiring invasive ventilation. Despite diaphragm being one of the target organ of the disease, no specific study has been done using ultrasound.We report diaphragm and lung ultrasound findings of a 13-month-old girl affected by SMARD1 (homozygosis c.1540G > A mutation in IGHMPB2 gene) with respiratory failure requiring permanent mechanical ventilation since birth and we discuss the role of diaphragmatic and lung ultrasound in this category of patients and its clinical implications.

Indexed as

DNA-Binding ProteinsTranscription FactorsAnimalsDiaphragmDyspneaFemaleHumansInfantLungMuscular Atrophy, SpinalPoint-of-Care SystemsRespiratory Distress Syndrome, NewbornDNA-Binding ProteinsTranscription FactorsDiaphragmDiaphragm functionDiaphragm ultrasoundJUSD-D-21–00,057Lung ultrasoundNeuromuscular disordersPersonalized medicinePrecision medicineSMARD1Spinal muscular atrophyUltrasound

Identifiers

PMID33847972
PMCPMC9148350
OpenAlexW3152750712

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.