Evidence map›Paper›PMID 33847884›Full record

ArticleEnvironmental science and pollution research international2021

Th1/Th2 imbalance and heat shock protein mediated inflammatory damage triggered by manganese via activating NF-κB pathway in chicken nervous system in vivo and in vitro.

Zhiying Miao, Kun Zhang, Rongkun Bao, Jingxin Li, You Tang, Xiaohua Teng

Abstract read
PubMed Publisher
In one paragraph

Article in Environmental science and pollution research international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 48 citations in OpenAlex.

  1. Article
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  4. Toxicology research · 2022
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  7. The Effect of DietaryLife (Basel, Switzerland) · 2022
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  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Zhiying Miao *Electrical and Information Engineering College, JiLin Agricultural Science and Technology University, Jilin, 132101, Jilin, China.
Kun Zhang *Heihe University, Heihe, 164300, People's Republic of China.
Rongkun BaoCollege of Veterinary Medicine, Northeast Agricultural University, Harbin, 150030, People's Republic of China.
Jingxin LiCollege of Animal Science and Technology, Northeast Agricultural University, Harbin, 150030, People's Republic of China.
You TangElectrical and Information Engineering College, JiLin Agricultural Science and Technology University, Jilin, 132101, Jilin, China. tangyou@neau.edu.cn.
Xiaohua TengElectrical and Information Engineering College, JiLin Agricultural Science and Technology University, Jilin, 132101, Jilin, China. tengxiaohua@neau.edu.cn.
Northeast Agricultural University · CNJilin Agricultural Science and Technology University · CNHeihe University · CN

Funding

National Natural Science Foundation of China No. 31972612
6 · The paper itself

Abstract

Manganese (Mn) is a ubiquitous heavy metal pollutant in environment, and excess Mn can damage nervous system of humans and animals. However, molecular mechanism of Mn-induced poultry neurotoxicity on inflammatory injury is still not fully clear. Thus, the purpose of the conducted research was to explore molecular mechanism of inflammatory injury caused by Mn in chicken nervous system. Two Mn poisoning models were established in vivo and in vitro. One hundred and eighty chickens were randomly separated into four groups. One control group was raised drinking water and standard diet. Three Mn groups were raised drinking water, and the standard diet supplemented with three different concentrations of MnCl

Indexed as

ChickensNF-kappa BAnimalsChick EmbryoHeat-Shock ProteinsManganeseNervous SystemHeat-Shock ProteinsManganeseNF-kappa BChicken nervous systemEnvironmental pollutant manganeseHeat shock proteinInflammatory injuryTh1/Th2 imbalance

Identifiers

PMID33847884
OpenAlexW3156850148

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.