Evidence map›Paper›PMID 33847565›Full record

ArticleeLife2021

Lipoprotein DolP supports proper folding of BamA in the bacterial outer membrane promoting fitness upon envelope stress.

David Ranava, Yiying Yang, Luis Orenday-Tapia, François Rousset, Catherine Turlan, Violette Morales, Lun Cui, Cyril Moulin, Carine Froment, Gladys Munoz and 6 more

Open access · goldAbstract read
In one paragraph

Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. A fluorescent reporter and single-turnover kinetics reveal insight into BAM complex function.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Overexpression of the Bam Complex Improves the Production ofInternational journal of molecular sciences · 2022
    Article
  13. BonA frommBio · 2021
    Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 2 institutions in 1 country.

David Ranava *Laboratoire de Microbiologie et Génétique Moléculaires (LMGM), Centre de Biologie Intégrative (CBI), Université de Toulouse, CNRS, UPS, Toulouse, France.ORCID 0000-0002-5841-7699
Yiying Yang *Laboratoire de Microbiologie et Génétique Moléculaires (LMGM), Centre de Biologie Intégrative (CBI), Université de Toulouse, CNRS, UPS, Toulouse, France.
Luis Orenday-Tapia *Laboratoire de Microbiologie et Génétique Moléculaires (LMGM), Centre de Biologie Intégrative (CBI), Université de Toulouse, CNRS, UPS, Toulouse, France.ORCID 0000-0002-1134-0823
François RoussetSynthetic Biology Group, Microbiology Department, Institut Pasteur, Paris, France.
Catherine TurlanLaboratoire de Microbiologie et Génétique Moléculaires (LMGM), Centre de Biologie Intégrative (CBI), Université de Toulouse, CNRS, UPS, Toulouse, France.
Violette MoralesLaboratoire de Microbiologie et Génétique Moléculaires (LMGM), Centre de Biologie Intégrative (CBI), Université de Toulouse, CNRS, UPS, Toulouse, France.
Lun CuiSynthetic Biology Group, Microbiology Department, Institut Pasteur, Paris, France.
Cyril MoulinLaboratoire de Microbiologie et Génétique Moléculaires (LMGM), Centre de Biologie Intégrative (CBI), Université de Toulouse, CNRS, UPS, Toulouse, France.
Carine FromentInstitut de Pharmacologie et de Biologie Structurale (IPBS), Université de Toulouse, CNRS, UPS, Toulouse, France.
Gladys MunozLaboratoire de Microbiologie et Génétique Moléculaires (LMGM), Centre de Biologie Intégrative (CBI), Université de Toulouse, CNRS, UPS, Toulouse, France.
Jérôme RechLaboratoire de Microbiologie et Génétique Moléculaires (LMGM), Centre de Biologie Intégrative (CBI), Université de Toulouse, CNRS, UPS, Toulouse, France.
Julien MarcouxInstitut de Pharmacologie et de Biologie Structurale (IPBS), Université de Toulouse, CNRS, UPS, Toulouse, France.ORCID 0000-0001-7321-7436
Anne Caumont-SarcosLaboratoire de Microbiologie et Génétique Moléculaires (LMGM), Centre de Biologie Intégrative (CBI), Université de Toulouse, CNRS, UPS, Toulouse, France.
Cécile AlbenneLaboratoire de Microbiologie et Génétique Moléculaires (LMGM), Centre de Biologie Intégrative (CBI), Université de Toulouse, CNRS, UPS, Toulouse, France.
David BikardSynthetic Biology Group, Microbiology Department, Institut Pasteur, Paris, France.ORCID 0000-0002-5729-1211
Raffaele IevaLaboratoire de Microbiologie et Génétique Moléculaires (LMGM), Centre de Biologie Intégrative (CBI), Université de Toulouse, CNRS, UPS, Toulouse, France.ORCID 0000-0002-3405-0650
Centre National de la Recherche Scientifique · FRInstitut Pasteur · FR

Funding

Agence Nationale de la Recherche ANR-10-INBS-08Agence Nationale de la Recherche ANR-10-LABX-62-IBEIDCentre National de la Recherche Scientifique ATIP-AvenirEuropean Research Council 677823Fondation pour la Recherche Médicale PostDoc Fellowship
6 · The paper itself

Abstract

In Proteobacteria, integral outer membrane proteins (OMPs) are crucial for the maintenance of the envelope permeability barrier to some antibiotics and detergents. In Enterobacteria, envelope stress caused by unfolded OMPs activates the sigmaE (σ

Indexed as

Bacterial Outer MembraneBacterial Outer Membrane ProteinsEscherichia coliEscherichia coli ProteinsGenetic FitnessLipoproteinsProtein FoldingBacterial Outer Membrane ProteinsBamA protein, E coliEscherichia coli ProteinsLipoproteinsBAMDolPE. coliEnvelope stressinfectious diseasemicrobiologyOMPsOuter membrane biogenesisYraP

Identifiers

PMID33847565
PMCPMC8081527
OpenAlexW3156965604

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.