Evidence map›Paper›PMID 33847459›Full record

ArticleAngewandte Chemie (International ed. in English)2021

Enantioselective Copper-Catalyzed Borylative Cyclization for the Synthesis of Quinazolinones.

Quentin Dherbassy, Srimanta Manna, Chunling Shi, Watcharapon Prasitwatcharakorn, Giacomo E M Crisenza, Gregory J P Perry, David J Procter

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Enantioselective Borylcupration/Cyclization of Alkene-Tethered Oxime Esters.Angewandte Chemie (International ed. in English) · 2025
    Article
  4. Article
  5. Review
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Quentin DherbassyDepartment of Chemistry, University of Manchester, Oxford Road, Manchester, M13 9PL, UK.
Srimanta MannaDepartment of Chemistry, University of Manchester, Oxford Road, Manchester, M13 9PL, UK.ORCID 0000-0002-3903-1256
Chunling ShiDepartment of Chemistry, University of Manchester, Oxford Road, Manchester, M13 9PL, UK.
Watcharapon PrasitwatcharakornDepartment of Chemistry, University of Manchester, Oxford Road, Manchester, M13 9PL, UK.
Giacomo E M CrisenzaDepartment of Chemistry, University of Manchester, Oxford Road, Manchester, M13 9PL, UK.ORCID 0000-0003-0622-2862
Gregory J P PerryDepartment of Chemistry, University of Manchester, Oxford Road, Manchester, M13 9PL, UK.ORCID 0000-0001-8173-3369
David J ProcterDepartment of Chemistry, University of Manchester, Oxford Road, Manchester, M13 9PL, UK.ORCID 0000-0003-3179-2509

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Quinazolinones are common substructures in molecules of medicinal importance. We report an enantioselective copper-catalyzed borylative cyclization for the assembly of privileged pyrroloquinazolinone motifs. The reaction proceeds with high enantio- and diastereocontrol, and can deliver products containing quaternary stereocenters. The utility of the products is demonstrated through further manipulations.

Indexed as

asymmetricboroncoppercyclizationnitrogen-containing heterocycles

Identifiers

PMID33847459
PMCPMC8252434

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.