Evidence map›Paper›PMID 33847158›Full record

ReviewAntioxidants & redox signaling2021

Role of Mitochondria-Derived Danger Signals Released After Injury in Systemic Inflammation and Sepsis.

Kiyoshi Itagaki, Ingred Riça, Barbora Konecna, Hyo In Kim, Jinbong Park, Elzbieta Kaczmarek, Carl J Hauser

Abstract readReview
In one paragraph

Review in Antioxidants & redox signaling, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  14. Can Neutrophils Prevent Nosocomial Pneumonia after Serious Injury?International journal of molecular sciences · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kiyoshi ItagakiDepartment of Surgery, Beth Israel Deaconess Medical Center/Harvard Medical School, Boston, Massachusetts, USA.ORCID 0000-0002-6033-1122
Ingred RiçaThe David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.
Barbora KonecnaInstitute of Molecular Biomedicine, Comenius University, Bratislava, Slovakia.
Hyo In KimDepartment of Surgery, Beth Israel Deaconess Medical Center/Harvard Medical School, Boston, Massachusetts, USA.
Jinbong ParkDepartment of Surgery, Beth Israel Deaconess Medical Center/Harvard Medical School, Boston, Massachusetts, USA.
Elzbieta KaczmarekDepartment of Surgery, Beth Israel Deaconess Medical Center/Harvard Medical School, Boston, Massachusetts, USA.
Carl J HauserDepartment of Surgery, Beth Israel Deaconess Medical Center/Harvard Medical School, Boston, Massachusetts, USA.

Funding

mtDAMPs and nosocomial pneumonia after injuryR03AI135346 · NIAID · BETH ISRAEL DEACONESS MEDICAL CENTER · PI ITAGAKI, KIYOSHI · 2018 to 2019
$175k
NIAID NIH HHS R03 AI135346
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsHumansMitochondriaSepsisSignal TransductionSystemic Inflammatory Response Syndromeinjuryinnate immunitymitochondrial DAMPsmitochondrial formyl peptidesneutrophils

Identifiers

PMID33847158
PMCPMC8905257

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.