Evidence map›Paper›PMID 33847150›Full record

Trial reportIntegrative cancer therapies

The Effectiveness of Qigong in Managing a Cluster of Symptoms (Breathlessness-Fatigue-Anxiety) in Patients with Lung Cancer: A Randomized Controlled Trial.

Alex Molassiotis, Dau Van Vu, Shirley Siu Yin Ching

3 registry-linked trialsOpen access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Integrative cancer therapies. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 25 papers, 15 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 15 pooled it
2.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02977845 nacompletednot on this map

Effect of Qigong on the Symptom Clusters of Dyspnea, Fatigue, and Anxiety.

TypeinterventionalSponsorNam Dinh University of NursingRan2017 to 2018Enrolled162ConditionsLung Cancer, Nonsmall Cell, Lung Cancer Non-Small Cell Stage 0, Lung Cancer, Nonsmall Cell, Stage I, Lung Cancer Non-Small Cell Stage IIArmsQigong
NCT06006221 nacompletednot on this map

The Effect of Qigong Intervention on State Anxiety Levels of Inpatiens in Psychiatric Wards: A Randomized Controlled Study

TypeinterventionalSponsorEmel Erdeniz GüreşRan2023 to 2023Enrolled70ConditionsPsychiatric DisorderArmsQi-gong relaxation exercise
NCT07315672 narecruitingnot on this map

Acupressure for Cough in Lung Cancer Survivors: A Randomized Controlled Trial

TypeinterventionalSponsorThe University of Hong KongRan2026 to 2027Enrolled80ConditionsLung Cancer (Diagnosis), Acupressure, Coughing, Symptom ClusterArmsacupressure, Education
3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 15 syntheses or guidelines pooled it, 39 citations in OpenAlex.

  1. Pooled it
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  5. Nonpharmacological dyspnoea-relief strategies in lung cancer: a systematic review and network meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2026
    Pooled it
  6. Pooled it
  7. Pooled it
  8. Pooled it
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  10. Mind-body interventions for cancer-related dyspnoea: a systematic review and meta-analysis of randomised controlled trials.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Pooled it
  11. Pooled it
  12. Pooled it
  13. Pooled it
  14. The effect of mind-body exercise in lung cancer patients: a meta-analysis of RCTs.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Pooled it
  15. Meditative movement for breathlessness in advanced COPD or cancer: a systematic review and meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2023
    Pooled it
  16. Trial
  17. Review
  18. Effect of Qigong exercise on quality of life and cortisol in patients with cancer: a non-randomized controlled trial.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Alex MolassiotisThe Hong Kong Polytechnic University, Hung Hom, Kowloon, Hksar, China.ORCID 0000-0001-6351-9991
Dau Van VuNam Dinh University of Nursing, Han Thuyen, Nam Dinh, Vietnam.ORCID 0000-0003-3088-7178
Shirley Siu Yin ChingThe Hong Kong Polytechnic University, Hung Hom, Kowloon, Hksar, China.
Hong Kong Polytechnic University · HKNam Dinh University of Nursing · VN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeQigong is used by cancer patients, but its effect is not adequately evaluated to date. The aim of this study was to investigate the effects of Qigong for the management of a symptom cluster comprising fatigue, dyspnea, and anxiety in patients with lung cancer. METHODOLOGY: A total of 156 lung cancer patients participated in this trial, and they were randomized to a Qigong group (6 weeks of intervention) or a waitlist control group receiving usual care. The symptom cluster was assessed at baseline, at the end of treatment (primary outcome), and at 12 weeks, alongside measures of cough and quality of life (QOL).

resultsThere was no significant interaction effect between group and time for the symptom cluster overall and for fatigue and anxiety. However, a significant trend towards improvement was observed on fatigue (

conclusionQigong did not alleviate the symptom cluster experience. Nevertheless, this intervention was effective in reducing dyspnea and cough, and improving QOL. More than 6 weeks were needed, however, for detecting the effect of Qigong on improving dyspnea. Furthermore, men benefited more than women. It may not be beneficial to use Qigong to manage the symptom cluster consisting of fatigue, dyspnea, and anxiety, but it may be effective in managing respiratory symptoms (secondary outcomes needing further verification in future research). Future studies targeting symptom clusters should ensure the appropriateness of the combination of symptoms.

trial registrationClinicalTrials.gov Identifier: NCT02977845. Registered November 30, 2016. https://clinicaltrials.gov/ct2/show/NCT02977845?term=Qigong&cond=Lung+Cancer&draw=2&rank=1.

Indexed as

Lung NeoplasmsQigongAnxietyDyspneaFatigueFemaleHumansMaleQuality of Lifeanxietycoughdyspneafatiguelung cancerQigongquality of life

Identifiers

PMID33847150
PMCPMC8047940
OpenAlexW3156971967

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.