Evidence map›Paper›PMID 33847141›Full record

ArticleJournal of the American Heart Association2021

Cardiac Morphology, Function, and Hemodynamics in Patients With Morbid Obesity and Nonalcoholic Steatohepatitis.

Grzegorz Styczynski, Piotr Kalinowski, Łukasz Michałowski, Rafał Paluszkiewicz, Bogna Ziarkiewicz-Wróblewska, Krzysztof Zieniewicz, Emanuel Tataj, Daniel Rabczenko, Cezary A Szmigielski, Maciej Sinski

Abstract read
In one paragraph

Article in Journal of the American Heart Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
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  4. Review
  5. Article
  6. Article
  7. Article
  8. Inhibition of visceral adipose tissue-derived pathogenic signals by activation of adenosine AAmerican journal of physiology. Gastrointestinal and liver physiology · 2024
    Article
  9. Article
  10. Review
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  13. The Liver and the Cardiovascular System: Two of a Kind?Journal of the American Heart Association · 2021
    Article
  14. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Grzegorz StyczynskiDepartment of Internal Medicine, Hypertension and Angiology Medical University of Warsaw Poland.
Piotr KalinowskiDepartment of General, Transplant and Liver Surgery Medical University of Warsaw Poland.
Łukasz MichałowskiDepartment of Pathology Centre for Biostructure Research Medical University of Warsaw Poland.
Rafał PaluszkiewiczDepartment of Internal Medicine, Hypertension and Angiology Medical University of Warsaw Poland.
Bogna Ziarkiewicz-WróblewskaDepartment of Pathology Centre for Biostructure Research Medical University of Warsaw Poland.
Krzysztof ZieniewiczDepartment of General, Transplant and Liver Surgery Medical University of Warsaw Poland.
Emanuel TatajDepartment of Medical Informatics and Telemedicine Medical University of Warsaw Poland.
Daniel RabczenkoDepartment of Monitoring and Analysis of Population Health Status National Institute of Public Health - National Institute of Hygiene Warsaw Poland.
Cezary A SzmigielskiDepartment of Internal Medicine, Hypertension and Angiology Medical University of Warsaw Poland.
Maciej SinskiDepartment of Internal Medicine, Hypertension and Angiology Medical University of Warsaw Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background The patients with nonalcoholic fatty liver disease demonstrate an increased cardiovascular risk. The adverse influence of liver abnormalities on cardiac function are among many postulated mechanisms behind this association. The aim of the study was to evaluate cardiac morphology and function in patients with morbid obesity referred for bariatric surgery with liver biopsy. Methods and Results We evaluated with echocardiography 171 consecutive patients without known cardiac disease (median age 42 [interquartile range, 37-48] years, median body mass index 43.7 [interquartile range, 41.0-47.5], 67% female patients. Based on the liver biopsy results, there were 44 patients with nonalcoholic steatohepatitis (NASH), 69 patients with isolated steatosis, and 58 patients without steatosis. Patients with NASH demonstrated signs of left ventricular concentric remodeling and hyperdynamic circulation, including indexed left ventricular end-diastolic diameter [cm/m

Indexed as

AdultBiopsyBody Mass IndexCardiovascular DiseasesDiastoleFemaleFollow-Up StudiesHeart VentriclesHemodynamicsHumansLiverMaleMiddle AgedNon-alcoholic Fatty Liver DiseaseObesity, MorbidRetrospective Studiescardiac remodelingechocardiographymetabolic syndrome

Identifiers

PMID33847141
PMCPMC8174163

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.