Evidence map›Paper›PMID 33846919›Full record

ArticleEnvironmental science and pollution research international2021

Antibiotic resistance and determination of resistant genes among cockle (Anadara granosa) isolates of Vibrio alginolyticus.

Safiyyah Shahimi, Aishah Elias, Sahilah Abd Mutalib, Mokry Salami, Fazlina Fauzi, Nurul Aqilah Mohd Zaini, Ma'aruf Abd Ghani, Ahmad Azuhairi

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Article in Environmental science and pollution research international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Molluscs-A ticking microbial bomb.Frontiers in microbiology · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Safiyyah ShahimiDepartment of Food Science, Faculty of Science and Technology, Universiti Kebangsaan Malaysia (UKM), UKM, 43600, Bangi, Malaysia.
Aishah EliasDepartment of Food Science, Faculty of Science and Technology, Universiti Kebangsaan Malaysia (UKM), UKM, 43600, Bangi, Malaysia.
Sahilah Abd MutalibDepartment of Food Science, Faculty of Science and Technology, Universiti Kebangsaan Malaysia (UKM), UKM, 43600, Bangi, Malaysia. sahilah@ukm.edu.my.
Mokry SalamiDepartment of Food Science, Faculty of Science and Technology, Universiti Kebangsaan Malaysia (UKM), UKM, 43600, Bangi, Malaysia.
Fazlina FauziDepartment of Food Science, Faculty of Science and Technology, Universiti Kebangsaan Malaysia (UKM), UKM, 43600, Bangi, Malaysia.
Nurul Aqilah Mohd ZainiDepartment of Food Science, Faculty of Science and Technology, Universiti Kebangsaan Malaysia (UKM), UKM, 43600, Bangi, Malaysia.
Ma'aruf Abd GhaniDepartment of Food Science, Faculty of Science and Technology, Universiti Kebangsaan Malaysia (UKM), UKM, 43600, Bangi, Malaysia.
Ahmad AzuhairiDepartment of Community Health, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, UPM, 43400, Serdang, Malaysia.
National University of Malaysia · MYUniversiti Putra Malaysia · MY

Funding

Universiti Kebangsaan Malaysia MI-2017-021
6 · The paper itself

Abstract

A total of 24 strains of Vibrio alginolyticus were isolated from cockles (Anadara granosa) and identified for VibA and gyrB genes. All V. alginolyticus isolates were then tested against nine different antibiotics. In this study, the highest percentage of antibiotic resistance was obtained against penicillin (37.50%), followed by ampicillin, vancomycin (12.50%) and erythromycin (8.33%). All of V. alginolyticus isolates were susceptible against streptomycin, kanamycin, tetracycline, chloramphenicol and sulfamethoxazole. Polymerase chain reaction (PCR) assay has confirmed the presence of four antibiotic resistance genes of penicillin (pbp2a), ampicillin (blaOXA), erythromycin (ermB) and vancomycin (vanB). Out of 24 V. alginolyticus isolates, 2 isolates possessed the tdh-related hemolysin (trh) (strains VA15 and VA16) and none for the thermostable direct hemolysin (tdh) gene. Both strains of the tdh-related hemolysin (trh) were susceptible to all antibiotics tested. The multiple antibiotic resistance (MAR) index ranging between 0.2 and 0.3 with 5 antibiograms (A1-A5) was observed. Combination of enterobacterial repetitive intergenic consensus-polymerase chain reaction (ERIC-PCR) and antibiotic resistance indicated 18 genome types which showed genetic heterogeneity of those V. alginolyticus isolates. The results demonstrated the presence of V. alginolyticus strain found in cockles can be a potential risk to consumers and can contribute to the deterioration of human health in the study area. Thus, it is essential for local authority to provide the preventive measures in ensuring the cockles are safe for consumption.

Indexed as

ArcidaeCardiidaeVibrio parahaemolyticusAnimalsAnti-Bacterial AgentsDrug Resistance, BacterialHumansMicrobial Sensitivity TestsVibrio alginolyticusAnti-Bacterial AgentsAntibiotic resistanceCockle (Anadara granosa)Enterobacterial repetitive intergenic consensus-polymerase chain reaction (ERIC-PCR)Molecular typingResistant genestdh and trh genesVibrio alginolyticus

Identifiers

PMID33846919
OpenAlexW3153931537

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.