ArticleMolecular imaging and biology2021
Reducing Radiation Exposure to Paediatric Patients Undergoing [18F]FDG-PET/CT Imaging.
Article in Molecular imaging and biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 33 citations in OpenAlex.
- How can children benefit from total-body PET?The British journal of radiology · 2026Review
- Total-body [European journal of nuclear medicine and molecular imaging · 2026Article
- Significant dose reduction employing dual-low-dose PET/CT in pediatric lymphoma: maintaining diagnostic, staging, and response-assessing efficacy.European radiology · 2026Article
- Assessment of reducedAnnals of nuclear medicine · 2025Article
- Thermogenic Activation of Adipose Tissue by Caffeine During Strenuous Exercising and Recovery: A Double-Blind Crossover Study.Metabolites · 2025Article
- CT-Free Attenuation Correction in Paediatric Long Axial Field-of-View Positron Emission Tomography Using Synthetic CT from Emission Data.Diagnostics (Basel, Switzerland) · 2024Article
- In vivo assessment of safety, biodistribution, and radiation dosimetry of the [EJNMMI research · 2024Article
- Reduced count pediatric whole-bodyPediatric radiology · 2024Article
- Analysis of image data from the EuroNet PHL-C2 trial indicates a potential reduction in injected F-18 FDG activities in children: a proposal to update the EANM Paediatric Dosage Card.European journal of nuclear medicine and molecular imaging · 2024Article
- EANM procedural recommendations for managing the paediatric patient in diagnostic nuclear medicine.European journal of nuclear medicine and molecular imaging · 2023Review
- Correlation of mean apparent diffusion coefficient (ADC) and maximal standard uptake value (SUVmax) evaluated by diffusion-weighted MRI and 18F-FDG-PET/CT in children with Hodgkin lymphoma: a feasibility study.Radiology and oncology · 2023Article
- Impact of radiation dose reduction and iterative image reconstruction on CT-guided spine biopsies.Scientific reports · 2023Article
- Ultra-low-dose CT reconstructed with the artificial intelligence iterative reconstruction algorithm (AIIR) inEJNMMI physics · 2023Article
- Image quality assessment along the one metre axial field-of-view of the total-body Biograph Vision Quadra PET/CT system forEJNMMI physics · 2022Article
- Evaluation of pediatric malignancies using total-body PET/CT with half-dose [European journal of nuclear medicine and molecular imaging · 2022Article
- The effect of modern PET technology and techniques on the EANM paediatric dosage card.European journal of nuclear medicine and molecular imaging · 2022Article
- A dedicated paediatric [EJNMMI research · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo investigate the possibility of reducing the injected activity for whole-body [18F]FDG-PET/CT studies of paediatric oncology patients and to assess the usefulness of time-of-flight (TOF) acquisition on PET image quality at reduced count levels. PROCEDURES: Twenty-nine paediatric oncology patients (12F/17M, 3-18 years old (median age 13y), weight 45±20 kg, BMI 19±4 kg/m
resultsThe visual inspection of the reconstructed images did not reveal significant differences in image quality between 75 and 100% count levels for PSF+TOF. The improvements in SNR and CNR were the greatest for TOF reconstruction and PSF combined. Both SNR and CNR gains did increase linearly with the patients BMI for both OSEM only and PSF reconstruction. These benefits were observed until reducing the counts to 50 and 35% for SNR and CNR, respectively.
conclusionsThe benefit of using TOF was noticeable when using 50% or greater of the counts when evaluating the CNR and SNR. For [18F]FDG-PET/CT, whole-body paediatric imaging the injected activity can be reduced to 75% of the original dose without compromising PET image quality.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.