Evidence map›Paper›PMID 33846875›Full record

ArticleJournal of behavioral medicine2021

Web-based cognitive behavior therapy for chronic pain patients with aberrant drug-related behavior: How did it work and for whom?

Haiyi Xie, Honoria Guarino, Sarah K Moore, Michelle Acosta, Alan J Budney, Andrew Rosenblum, Lisa A Marsch, Chunki Fong

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of behavioral medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Article
  6. Observational
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Haiyi XieDepartment of Biomedical Data Science, Geisel School of Medicine at Dartmouth College, Hanover, NH, USA. Haiyi.Xie@dartmouth.edu.ORCID 0000-0003-4549-879X
Honoria GuarinoGraduate School of Public Health and Health Policy, City University of New York, New York, NY, USA.
Sarah K MooreCenter for Technology and Behavioral Health, Geisel School of Medicine at Dartmouth College, Lebanon, NH, USA.
Michelle AcostaGraduate School of Public Health and Health Policy, City University of New York, New York, NY, USA.
Alan J BudneyDepartment of Psychiatry, Geisel School of Medicine at Dartmouth College, Hanover, NH, USA.
Andrew RosenblumNDRI-USA, New York, NY, USA.
Lisa A MarschDepartment of Psychiatry, Geisel School of Medicine at Dartmouth College, Hanover, NH, USA.
Chunki FongGraduate School of Public Health and Health Policy, City University of New York, New York, NY, USA.
Dartmouth College · USCity University of New York · US

Funding

Treatment Development & Evaluation CoreP30DA029926 · NIDA · DARTMOUTH COLLEGE · PI Lisa A. Marsch · 2011 to 2026
$21.5M
Web-based CBT for Opioid-treated, Chronic Pain Patients with Aberrant BehaviorR01DA026887 · NIDA · NATIONAL DEVELOPMENT AND RESEARCH INSTITUTES, INC. · PI MARSCH, LISA A., ROSENBLUM, ANDREW BRUCE · 2010 to 2013
$2.3M
NIDA NIH HHS P30 DA029926NIDA NIH HHS P30DA029926NIDA NIH HHS R01 DA026887NIDA NIH HHS R01DA026887
6 · The paper itself

Abstract

This study explored mediating pathways, moderating factors, and moderated mediation effects of a web-based, cognitive behavioral therapy (CBT) intervention for chronic pain patients with aberrant drug-related behavior (ADRB). In a 2-arm RCT, patients with chronic pain who screened positive for ADRB received treatment-as-usual (TAU, n = 55) or TAU plus a 12-week, web-based CBT intervention (n = 55). Assessments were conducted at weeks 4, 8, and 12, and at 1- and 3-months post intervention. Web-CBT significantly reduced pain catastrophizing, which, in turn, reduced pain interference and pain severity via a pathway of pain catastrophizing. Web-CBT also significantly reduced ADRB both directly and indirectly by reducing pain catastrophizing. For pain interference and pain severity, web-CBT was more effective than TAU for younger patients (≤ age 50). For pain severity, web-CBT was more effective for both younger patients (≤ age 50), and those with a lifetime substance use disorder. Findings suggest that web-CBT's positive impact on pain outcomes and ADRB are mediated by its effect on pain catastrophizing, and its treatment effects may be most robust for younger patients and those with histories of substance dependence.

Indexed as

Chronic PainCognitive Behavioral TherapyPharmaceutical PreparationsCatastrophizationHumansInternetMiddle AgedTreatment OutcomePharmaceutical PreparationsChronic painCognitive behavior therapy (CBT)MediationModeration and moderated mediation analysisOpioid use disorderWeb-based interventions

Identifiers

PMID33846875
PMCPMC8658745
OpenAlexW3153129757

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.