ArticlePediatric research2022
Defining values for controlled attenuation parameter and liver stiffness in youth without liver disease.
Article in Pediatric research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- hs-CRP as a Marker of Systemic Low-Grade Inflammation Is Not Associated with Steatotic Liver Disease in Adolescents: Insights from the EVA4YOU Study.Metabolites · 2026Article
- Clinical research of fibroscan ‒ TE-CAP at noninvasive diagnosis of hepatic steatosis in children.Clinics (Sao Paulo, Brazil) · 2024Article
- Diagnostic indicators and lifestyle interventions of metabolic-associated fatty liver disease.Frontiers in nutrition · 2024Review
- Article
- Determinants of non-alcoholic fatty liver disease in young people: Maternal, neonatal, and adolescent factors.PloS one · 2024Article
- Association between hypertension and the prevalence of liver steatosis and fibrosis.BMC endocrine disorders · 2023Article
- Article
- Association between type 2 diabetes status and prevalence of liver steatosis and fibrosis among adults aged ≥ 40 years.BMC endocrine disorders · 2022Article
- Pediatric percentiles for transient elastography measurements - effects of age, sex, weight status and pubertal stage.Frontiers in endocrinology · 2022Article
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWe aimed to determine the reference values to define an age-specific normal range of controlled attenuation parameter (CAP, a measure of liver steatosis) and liver stiffness measurement (LSM) values assessed by ultrasound-based transient elastography in adolescents without underlying liver disease.
methodsA total of 462 participants were included in this cross-sectional study using data from NHANES 2017-2018. LSM and CAP were carried out using the FibroScan® M-probe. Anthropometric, metabolic and hematological parameters were measured.
resultsThe median CAP was 199.0 dB/m (150.0-245.0 dB/m, 10th to 90th percentiles) and the median LSM was 4.7 kPa (3.4-6.3 kPa, 10th to 90th percentiles) for ages 12-19.9 years. Regression analyses show that the CAP and LSM were not positively correlated with age (boys CAP R
conclusionsThe reference values indicated here for LSM and CAP will help in the screening of adolescents between ages 12 and 19.9 years and might serve as a useful method for identifying those youth at high risk of nonalcoholic fatty liver disease. IMPACT: The reference values indicated in this study for liver stiffness measurement (LSM) and controlled attenuation parameter (CAP) will help in the screening of adolescents between ages 12 and 19.9 years in clinical practice. The cutoffs of LSM and CAP might serve as a useful method for identifying those youth at high risk of nonalcoholic fatty liver disease.
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