ArticleScientific reports2021
The quantitative comparison between high wall shear stress and high strain in the formation of paraclinoid aneurysms.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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11 citing papers in PubMed, 23 citations in OpenAlex.
- Correlation between computational fluid dynamics-derived low wall shear stress and vessel wall enhancement on high-resolution MR vessel wall imaging in intracranial aneurysms.European radiology · 2026Article
- Toward Patient-Specific Hemodynamic Decision-Making in Cerebral Aneurysms: The Maturation of Computational Fluid Dynamics and Fluid-Structure Interaction.Neurointervention · 2026Article
- Novel morphological indexes for quantitative evaluation of cerebral aneurysm irregularity.Scientific reports · 2025Article
- Investigation of paraclinoid aneurysm formation by comparing the combined influence of hemodynamic parameters between aneurysmal and non-aneurysmal arteries.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2024Article
- Influence of circle of Willis modeling on hemodynamic parameters in anterior communicating artery aneurysms and recommendations for model selection.Scientific reports · 2024Article
- Stent-assisted coiling of unruptured paraclinoid aneurysms with wide neck or unfavorable dome-to-neck ratio: Results of ventral wall vs dorsal wall with propensity score matching analysis.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2024Article
- Morphology and Hemodynamics of Cerebral Arteries and Aneurysms in a Rare Pair of Monozygotic Twins.Diagnostics (Basel, Switzerland) · 2023Article
- The Current Limitations and Advanced Analysis of Hemodynamic Study of Cerebral Aneurysms.Neurointervention · 2023Review
- Influence of hydrodynamic and functional nonlinearities of blood flow in the cerebral vasculature on cerebral perfusion and autoregulation pressure reserve.Scientific reports · 2023Article
- Physiologic Flow Diversion Coiling Technique for Wide-Necked Aneurysms with an Asymmetric Bidirectional Flow at the Aneurysm Neck.Neurointervention · 2022Article
- Heterogeneous Maturation of Arterio-Venous Fistulas and Loop-Shaped Venous Interposition Grafts: A Histological and 3D Flow Simulation Comparison.Biomedicines · 2022Article
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Authors and funding
5 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In the hemodynamic study, computational fluid dynamics (CFD) analysis has shown that high wall shear stress (WSS) is an important parameter in cerebral aneurysm formation. However, CFD analysis is not more realistic than fluid-structure interaction (FSI) analysis given its lack of considering the involvement of vascular structures. To investigate the relationship between the hemodynamic parameters and the aneurysm formation, the locations of high WSS and high strain were extracted from the CFD and FSI analyses, respectively. Then the distances between the aneurysm formation site and the locations of high WSS or high strain were calculated. A total of 37 intracranial paraclinoid aneurysms were enrolled for quantitative comparison. Additionally, the dura mater was modeled to facilitate realistic results in FSI analysis. The average distance from the location of the aneurysm formation site to the high strain (1.74 mm [Formula: see text] 1.04 mm) was smaller than the average distance to the high WSS (3.33 mm [Formula: see text] 1.18 mm). The presence of dura mater also influenced the findings in the aneurysm formation site. High strain extracted by FSI analysis is an important hemodynamic factor related to the formation of cerebral aneurysms. Strain parameter could help to predict the formation of aneurysms and elucidate the appropriate treatment.
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