ArticleScientific reports2021
Comprehensive surgical treatment strategy for spinal metastases.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 3 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 3 syntheses or guidelines pooled it, 50 citations in OpenAlex.
- Carbon fiber-reinforced polyetheretherketone implants versus titanium implants for spinal tumors: a systematic review and meta-analysis.Journal of neuro-oncology · 2026Pooled it
- Magnetic resonance-guided focused ultrasound versus percutaneous thermal ablation in local control of bone oligometastases: a systematic review and meta-analysis.La Radiologia medica · 2024Pooled it
- Treatment progress of spinal metastatic cancer: a powerful tool for improving the quality of life of the patients.Journal of orthopaedic surgery and research · 2023Pooled it
- Regional variability and economic impact on surgical practices for metastatic spinal disease in Europe - a survey on spine surgeons.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Surgical Treatment of Spinal Metastases-A Retrospective Single-Center Study of 268 Patients.Journal of clinical medicine · 2025Article
- Combined Rigid-Flexible Multibody Analysis Reveals Reduced Pedicle Screw Loads in Short-Segment Fixation for Decompressed Lumbar Spine Stabilization.Annals of biomedical engineering · 2025Article
- Incidence of and survival after surgery for metastatic spine disease: a nationwide register-based study between 1997 and 2020 from Finland.Acta orthopaedica · 2025Article
- Artificial intelligence in neurovascular decision-making: a comparative analysis of ChatGPT-4 and multidisciplinary expert recommendations for unruptured intracranial aneurysms.Neurosurgical review · 2025Article
- Spinal metastases at the thoracolumbar junction - Influencing factors for surgical decision-making according to a multicentric registry.Brain & spine · 2025Article
- Extensive thoracic vertebral and chest wall metastases as the initial presentation of breast cancer: a case report and literature review.Frontiers in oncology · 2025Review
- Effects of sarcopenia and nutritional status on surgical outcomes for metastatic spinal tumors: In the perspective of peri-operative complications and performance improvement.Acta neurochirurgica · 2024Article
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- Expected motor function change following decompressive surgery for spinal metastatic disease.North American Spine Society journal · 2023Article
- Percutaneous lumbopelvic fixation for pathologic sacral fractures and spinopelvic dissociation: patient series.Journal of neurosurgery. Case lessons · 2023Article
- Spinal tumours: recommendations of the Polish Society of Spine Surgery, the Polish Society of Oncology, the Polish Society of Neurosurgeons, the Polish Society of Oncologic Surgery, the Polish Society of Oncologic Radiotherapy, and the Polish Society of Orthopaedics and Traumatology.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2023Article
- Cross-link augmentation enhances CFR-PEEK short fixation in lumbar metastasis stabilization.Frontiers in bioengineering and biotechnology · 2023Article
- Risk-adapted stereotactic body radiotherapy for patients with cervical spinal metastases.Cancer science · 2022Article
- CFR-PEEK Pedicle Screw Instrumentation for Spinal Neoplasms: A Single Center Experience on Safety and Efficacy.Cancers · 2022Article
- Osteolytic vs. Osteoblastic Metastatic Lesion: Computational Modeling of the Mechanical Behavior in the Human Vertebra after Screws Fixation Procedure.Journal of clinical medicine · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The management of patients with spinal metastases (SM) requires a multidisciplinary team of specialists involved in oncological care. Surgical management has evolved significantly over the recent years, which warrants reevaluation of its role in the oncological treatment concept. Any patient with a SM was screened for study inclusion. We report baseline characteristics, surgical procedures, complication rates, functional status and outcome of a large consecutive cohort undergoing surgical treatment according to an algorithm. 667 patients underwent 989 surgeries with a mean age of 65 years (min/max 20-94) between 2007 and 2018. The primary cancers mostly originated from the prostate (21.7%), breast (15.9%) and lung (10.0%). Surgical treatment consisted of dorsoventral stabilization in 69.5%, decompression without instrumentation in 12.5% and kyphoplasty in 18.0%. Overall survival reached 18.4 months (95% CI 9.8-26.9) and the median KPS increased by 10 within hospital stay. Surgical management of SMs should generally represent the first step of a conclusive treatment algorithm. The need to preserve long-term symptom control and biomechanical stability requires a surgical strategy currently not supported by level I evidence.
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Registered trials
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