Evidence map›Paper›PMID 33846411›Full record

ArticleScientific reports2021

Constitutive depletion of Slc34a2/NaPi-IIb in rats causes perinatal mortality.

Eva Maria Pastor-Arroyo, Josep M Monné Rodriguez, Giovanni Pellegrini, Carla Bettoni, Moshe Levi, Nati Hernando, Carsten A Wagner

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Pharmacology of Mammalian NaHandbook of experimental pharmacology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Eva Maria Pastor-ArroyoInstitute of Physiology, University of Zürich, Winterthurerstrasse 190, 8057, Zurich, Switzerland.
Josep M Monné RodriguezLaboratory for Animal Model Pathology (LAMP), Institute of Veterinary Pathology, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 268, 8057, Zurich, Switzerland.
Giovanni PellegriniLaboratory for Animal Model Pathology (LAMP), Institute of Veterinary Pathology, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 268, 8057, Zurich, Switzerland.
Carla BettoniInstitute of Physiology, University of Zürich, Winterthurerstrasse 190, 8057, Zurich, Switzerland.
Moshe LeviDepartment of Biochemistry and Molecular and Cellular Biology, Georgetown University, Washington, DC, USA.
Nati HernandoInstitute of Physiology, University of Zürich, Winterthurerstrasse 190, 8057, Zurich, Switzerland. hernando@physiol.uzh.ch.
Carsten A WagnerInstitute of Physiology, University of Zürich, Winterthurerstrasse 190, 8057, Zurich, Switzerland. wagnerca@access.uzh.ch.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Absorption of dietary phosphate (Pi) across intestinal epithelia is a regulated process mediated by transcellular and paracellular pathways. Although hyperphosphatemia is a risk factor for the development of cardiovascular disease, the amount of ingested Pi in a typical Western diet is above physiological needs. While blocking intestinal absorption has been suggested as a therapeutic approach to prevent hyperphosphatemia, a complete picture regarding the identity and regulation of the mechanism(s) responsible for intestinal absorption of Pi is missing. The Na

Indexed as

AnimalsAnimals, NewbornBody WeightCalciumCreatinineEmbryo, MammalianFecesFemaleFibroblast Growth Factor-23Fibroblast Growth FactorsHeterozygoteHomozygoteMaleOrgan SpecificityPhosphatesRatsCalciumCreatinineFibroblast Growth Factor-23Fibroblast Growth FactorsPhosphatesSodium-Phosphate Cotransporter Proteins, Type IIb

Identifiers

PMID33846411
PMCPMC8042035

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.