Evidence map›Paper›PMID 33846394›Full record

ArticleScientific reports2021

Efficacy of broflanilide (VECTRON T500), a new meta-diamide insecticide, for indoor residual spraying against pyrethroid-resistant malaria vectors.

Corine Ngufor, Renaud Govoetchan, Augustin Fongnikin, Estelle Vigninou, Thomas Syme, Martin Akogbeto, Mark Rowland

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
6.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 49 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Corine NguforLondon School of Hygiene and Tropical Medicine (LSHTM), London, UK. corine.ngufor@lshtm.ac.uk.
Renaud GovoetchanLondon School of Hygiene and Tropical Medicine (LSHTM), London, UK.
Augustin FongnikinCentre de Recherche Entomologiques de Cotonou (CREC), Cotonou, Benin.
Estelle VigninouCentre de Recherche Entomologiques de Cotonou (CREC), Cotonou, Benin.
Thomas SymeLondon School of Hygiene and Tropical Medicine (LSHTM), London, UK.
Martin AkogbetoCentre de Recherche Entomologiques de Cotonou (CREC), Cotonou, Benin.
Mark RowlandLondon School of Hygiene and Tropical Medicine (LSHTM), London, UK.
London School of Hygiene & Tropical Medicine · GBAidjan-Lagos Corridor Organization · BJ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The rotational use of insecticides with different modes of action for indoor residual spraying (IRS) is recommended for improving malaria vector control and managing insecticide resistance. Insecticides with new chemistries are urgently needed. Broflanilide is a newly discovered insecticide under consideration. We investigated the efficacy of a wettable powder (WP) formulation of broflanilide (VECTRON T500) for IRS on mud and cement wall substrates in laboratory and experimental hut studies against pyrethroid-resistant malaria vectors in Benin, in comparison with pirimiphos-methyl CS (Actellic 300CS). There was no evidence of cross-resistance to pyrethroids and broflanilide in CDC bottle bioassays. In laboratory cone bioassays, broflanilide WP-treated substrates killed > 80% of susceptible and pyrethroid-resistant An. gambiae sl for 6-14 months. At application rates of 100 mg/m

Indexed as

AnimalsAnophelesBeninBenzamidesBiological AssayFluorocarbonsInsecticide ResistanceInsecticidesMalariaMosquito VectorsPyrethrinsWorld Health Organization3-benzamido-N-(4-(perfluoropropan-2-yl)phenyl)benzamideBenzamidesFluorocarbonsInsecticidesPyrethrins

Identifiers

PMID33846394
PMCPMC8042056
OpenAlexW3099117827

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.