ArticleNature communications2021
Autophagy of the m
Open access · goldAbstract read
In one paragraph
Article in Nature communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
70citing papers in PubMed, 1 pooled it
7.7field-weighted citation impact, top 2% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
70 citing papers in PubMed, 1 synthesis or guideline pooled it, 123 citations in OpenAlex.
- Prognostic and clinicopathological value of m6A regulators in human cancers: a meta-analysis.Aging · 2022Pooled it
- Arsenic disrupts autophagosome-lysosome fusion in a zinc dependent manner across multiple human skin and lung cells lines.Archives of toxicology · 2026Article
- FTO-ACKR3 Axis Regulates Polycyclic Aromatic Hydrocarbons-Induced Asthma Attacks via AhR-Mediated mEnvironment & health (Washington, D.C.) · 2026Article
- Novel role of FTO in regulation of gut-brain communication viaGut microbes · 2025Article
- YTHDF2 regulates self non-coding RNA metabolism to control inflammation and tumorigenesis.Nature communications · 2025Article
- Hypoxia-induced degradation of FTO promotes apoptosis by unmasking RACK1-mediated activation of MTK1-JNK1/2 pathway.Journal of advanced research · 2025Article
- Arsenic regulates ALKBH1 abundance and substrate specificity to promote translation and tumorigenicity.Cell reports · 2025Article
- SSB cooperates with METTL16-mediated mCell reports · 2025Article
- Helicobacter pylori CagA elevates FTO to induce gastric cancer progression via a "hit-and-run" paradigm.Cancer communications (London, England) · 2025Article
- RNA NCell death & disease · 2025Article
- NZhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2025Review
- FTO suppresses DNA repair by inhibiting PARP1.Nature communications · 2025Article
- MAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- FTO effects the proliferation, invasion, and glycolytic metabolism of colon cancer by regulating PKM2.Journal of cancer research and clinical oncology · 2025Article
- Epigenetic orchestration of RNA mInternational journal of biological sciences · 2025Review
- Targeting DTX2/UFD1-mediated FTO degradation to regulate antitumor immunity.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Emerging roles of NHeliyon · 2024Review
- (-)-Epigallocatechin 3-gallate protects pancreatic β-cell against excessive autophagy-induced injury through promoting FTO degradation.Autophagy · 2024Article
- Research progress on the regulatory mechanism of cell senescence in arsenic toxicity: a systematic review.Toxicology research · 2024Review
- The tumor-intrinsic role of the mScience immunology · 2024Article
10 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 4 institutions in 2 countries.
Yan-Hong Cui *Department of Medicine, Section of Dermatology, University of Chicago, Chicago, IL, USA.ORCID 0000-0002-4169-6521
Seungwon Yang *Department of Medicine, Section of Dermatology, University of Chicago, Chicago, IL, USA.ORCID 0000-0002-8970-7373
Jiangbo Wei *Departments of Chemistry, Department of Biochemistry and Molecular Biology, Institute for Biophysical Dynamics, University of Chicago, Chicago, IL, USA.ORCID 0000-0003-2691-6490
Christopher R SheaDepartment of Medicine, Section of Dermatology, University of Chicago, Chicago, IL, USA.
Wen ZhongDepartment of Medicine, Section of Dermatology, University of Chicago, Chicago, IL, USA.
Fang WangDepartment of Medicine, Section of Dermatology, University of Chicago, Chicago, IL, USA.
Palak ShahDepartment of Medicine, Section of Dermatology, University of Chicago, Chicago, IL, USA.ORCID 0000-0002-6142-5630
Muhammad G KibriyaInstitute for Population and Precision Health, Department of Public Health Sciences, The University of Chicago, Chicago, IL, USA.
Xiaolong CuiDepartments of Chemistry, Department of Biochemistry and Molecular Biology, Institute for Biophysical Dynamics, University of Chicago, Chicago, IL, USA.ORCID 0000-0002-1345-2271
Habibul AhsanInstitute for Population and Precision Health, Department of Public Health Sciences, The University of Chicago, Chicago, IL, USA.
Chuan HeDepartments of Chemistry, Department of Biochemistry and Molecular Biology, Institute for Biophysical Dynamics, University of Chicago, Chicago, IL, USA.ORCID 0000-0003-4319-7424
Yu-Ying HeDepartment of Medicine, Section of Dermatology, University of Chicago, Chicago, IL, USA. yyhe@medicine.bsd.uchicago.edu.ORCID 0000-0002-2665-7962
University of Chicago · USChicago Department of Public Health · USHoward Hughes Medical Institute · USUniversity of Michigan · US
Funding
VIRAL ONCOLOGY CORE FACILITYP30CA014599 · NCI · UNIVERSITY OF CHICAGO · PI CHIEN-MIN KAO · 1985 to 2026
$122.1MRe-Engineering Translational Research at the University of ChicagoUL1TR000430 · NCATS · UNIVERSITY OF CHICAGO · PI SOLWAY, JULIAN · 2012 to 2016
$20.2MPilot Program CoreP30ES027792 · NIEHS · UNIVERSITY OF CHICAGO · PI Gokhan M. Mutlu, Gail S Prins · 2017 to 2026
$13.6MYTHDF2 and UVB damage response in skin cancerR01ES024373 · NIEHS · UNIVERSITY OF CHICAGO · PI HE, YU-YING · 2015 to 2023
$4.3MThe mechanistic role of METTL14 in UVB-induced skin tumorigenesisR01ES030576 · NIEHS · UNIVERSITY OF CHICAGO · PI HE, YU-YING · 2019 to 2023
$3.0MDirect Oxidative Nucleic Acids DemethylationR01ES030546 · NIEHS · UNIVERSITY OF CHICAGO · PI HE, CHUAN · 2019 to 2023
$1.9MFTO and RNA methylation in arsenic tumorigenicityR01ES031534 · NIEHS · UNIVERSITY OF CHICAGO · PI HE, YU-YING · 2020 to 2022
$1.2MHoward Hughes Medical InstituteNCATS NIH HHS UL1 TR000430NCI NIH HHS P30 CA014599NIEHS NIH HHS P30 ES027792NIEHS NIH HHS R01 ES024373NIEHS NIH HHS R01 ES030546NIEHS NIH HHS R01 ES030576NIEHS NIH HHS R01 ES031534
Abstract
Here we show that FTO as an N
Indexed as
AutophagyAdenosineAlpha-Ketoglutarate-Dependent Dioxygenase FTOAnimalsArsenicBase SequenceCarcinogenesisCell Transformation, NeoplasticDown-RegulationEpidermisGene OntologyHaCaT CellsHEK293 CellsHumansKeratinocytesLysosomesAdenosineAlpha-Ketoglutarate-Dependent Dioxygenase FTOArsenicFTO protein, humanNedd4L protein, humanNedd4 Ubiquitin Protein LigasesNF-kappa BN-methyladenosineRNA, MessengerSequestosome-1 ProteinSQSTM1 protein, humanTumor Necrosis Factor-alpha
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.