Evidence map›Paper›PMID 33846222›Full record

ArticleOpen heart2021

Surgical treatment for infective endocarditis in the ageing society: a nationwide retrospective study in Japan.

Hiroyuki Kiriyama, Hidehiro Kaneko, Hidetaka Itoh, Tatsuya Kamon, Kojiro Morita, Taisuke Jo, Katsuhito Fujiu, Masao Daimon, Norifumi Takeda, Hiroyuki Morita and 2 more

Open access · goldAbstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Open heart, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Infective Endocarditis in the Elderly: Challenges and Strategies.Journal of cardiovascular development and disease · 2022
    Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Hiroyuki KiriyamaDepartment of Cardiovascular Medicine, The University of Tokyo, Bunkyo-ku, Japan kiriyaman0427@gmail.com.ORCID 0000-0001-9663-3141
Hidehiro KanekoDepartment of Cardiovascular Medicine, The University of Tokyo, Bunkyo-ku, Japan.ORCID 0000-0003-2553-6170
Hidetaka ItohDepartment of Cardiovascular Medicine, The University of Tokyo, Bunkyo-ku, Japan.
Tatsuya KamonDepartment of Cardiovascular Medicine, The University of Tokyo, Bunkyo-ku, Japan.
Kojiro MoritaDepartment of Clinical Epidemiology and Health Economics, School of Public Health, The University of Tokyo, Bunkyo-ku, Japan.
Taisuke JoDepartment of Health Services Research, The University of Tokyo, Bunkyo-ku, Japan.
Katsuhito FujiuDepartment of Cardiovascular Medicine, The University of Tokyo, Bunkyo-ku, Japan.
Masao DaimonDepartment of Cardiovascular Medicine, The University of Tokyo, Bunkyo-ku, Japan.
Norifumi TakedaDepartment of Cardiovascular Medicine, The University of Tokyo, Bunkyo-ku, Japan.
Hiroyuki MoritaDepartment of Cardiovascular Medicine, The University of Tokyo, Bunkyo-ku, Japan.
Hideo YasunagaDepartment of Clinical Epidemiology and Health Economics, School of Public Health, The University of Tokyo, Bunkyo-ku, Japan.
Issei KomuroDepartment of Cardiovascular Medicine, The University of Tokyo, Bunkyo-ku, Japan.
The University of Tokyo · JPUniversity of Tsukuba · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe current status of surgical treatment for infective endocarditis (IE) among very elderly people is unclear.

methodsWe extracted data on patients in Japan with community-acquired IE who were admitted and discharged between April 2010 and February 2018 using a nationwide inpatient, the Diagnosis Procedure Combination database. We divided patients into three groups: non-elderly (<65 years), elderly (65-79 years) and very elderly (≥80 years). A 1:1 propensity score matching was performed to compare proportions of surgical treatment and in-hospital mortality among the groups.

resultsWe identified 20 667 eligible patients (median age 70 years, 61.0% men). The proportion of very elderly patients significantly increased (19.1% in 2010 to 29.7% in 2018). The proportion of surgical treatment was significantly lower, and in-hospital mortality was significantly higher in very elderly patients. This tendency was more pronounced among patients with in-hospital complications such as heart failure, stroke or embolism. Surgical treatment was significantly associated with lower in-hospital mortality even in very elderly patients, both in an unmatched (OR 0.61; 95% CI 0.47 to 0.78) and a propensity score matched cohort (OR 0.61; 95% CI 0.43 to 0.85).

conclusionsThe proportion of very elderly patients with IE was increasing, and very elderly patients had higher in-hospital mortality. The proportion of surgical treatment for IE among very elderly patients was low, but it was associated with lower in-hospital mortality. Further studies are needed to establish the optimal strategy for IE among very elderly patients.

Indexed as

AgingPropensity ScoreAdultAgedAged, 80 and overAge DistributionAge FactorsData ManagementEndocarditisFollow-Up StudiesHeart Valve ProsthesisHumansJapanMiddle AgedPrognosisProsthesis-Related Infectionsendocarditisepidemiologyheart valve prosthesis implantation

Identifiers

PMID33846222
PMCPMC8047992
OpenAlexW3157015412

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.