Evidence map›Paper›PMID 33846129›Full record

ArticleAntimicrobial agents and chemotherapy2021

Experience with Liposomal Amphotericin B in Outpatient Parenteral Antimicrobial Therapy.

Yvonne J Burnett, Andrej Spec, Mohamed M Ahmed, William G Powderly, Yasir Hamad

Open access · greenAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. A Bundle of the Top 10 OPAT Publications in 2021.Open forum infectious diseases · 2022
    Article
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Yvonne J BurnettDepartment of Pharmacy Practice, St. Louis College of Pharmacy at the University of Health Sciences and Pharmacy in St. Louis, St. Louis, Missouri, USA Yvonne.burnett@uhsp.edu.ORCID 0000-0003-1114-3421
Andrej SpecDivision of Infectious Diseases, Washington University School of Medicine in St. Louis, St. Louis, Missouri, USA.ORCID 0000-0001-7612-4710
Mohamed M AhmedDepartment of Nephrology, Medical University of South Carolina, Charleston, South Carolina, USA.
William G PowderlyDivision of Infectious Diseases, Washington University School of Medicine in St. Louis, St. Louis, Missouri, USA.
Yasir HamadDivision of Infectious Diseases, Washington University School of Medicine in St. Louis, St. Louis, Missouri, USA.ORCID 0000-0001-6616-7127
Washington University in St. Louis · USMedical University of South Carolina · USUniversity of Health Sciences and Pharmacy · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Outpatient parenteral antimicrobial therapy (OPAT) is a safe, effective, and convenient treatment strategy for patients receiving intravenous antimicrobials in the outpatient setting; however, data are limited describing the use and safety of liposomal amphotericin B (L-AMB). Records of patients receiving L-AMB OPAT between 1/1/2015 and 7/31/2018 were retrospectively reviewed. The primary objective was to describe the OPAT patient population discharged on L-AMB and evaluate factors associated with readmission and adverse events (AEs). Analysis was performed to evaluate for predictors of worse outcomes. Forty-two patients (67% male, median age 50 years) were identified, most of whom were treated for histoplasmosis. The most common doses of L-AMB were 3 mg/kg (

Indexed as

Anti-Infective AgentsOutpatientsAmphotericin BAntifungal AgentsFemaleHumansMaleMiddle AgedRetrospective StudiesAmphotericin BAntifungal AgentsAnti-Infective Agentsliposomal amphotericin BamphotericinhypokalemianephrotoxicityOPAToutpatient

Identifiers

PMID33846129
PMCPMC8316037
OpenAlexW3151255820

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.