Evidence map›Paper›PMID 33846120›Full record

ArticleInfection and immunity2021

The Diadenylate Cyclase CdaA Is Critical for Borrelia turicatae Virulence and Physiology.

Clay D Jackson-Litteken, C Tyler Ratliff, Alexander R Kneubehl, Cheta Siletti, Lindsay Pack, Renny Lan, TuAnh N Huynh, Job E Lopez, Jon S Blevins

Open access · hybridAbstract read
In one paragraph

Article in Infection and immunity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. TheInfection and immunity · 2026
    Article
  3. Regulation of potassium homeostasis inFrontiers in microbiology · 2026
    Article
  4. Article
  5. Article
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Clay D Jackson-LittekenDepartment of Microbiology and Immunology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
C Tyler RatliffDepartment of Microbiology and Immunology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
Alexander R KneubehlSection of Tropical Medicine, Department of Pediatrics, Baylor College of Medicine and Texas Children's Hospital, Houston, Texas, USA.
Cheta SilettiFood Science Department, University of Wisconsin-Madison, Madison, Wisconsin, USA.ORCID 0000-0002-4524-0556
Lindsay PackArkansas Children's Nutrition Center, Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
Renny LanArkansas Children's Nutrition Center, Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
TuAnh N HuynhFood Science Department, University of Wisconsin-Madison, Madison, Wisconsin, USA.ORCID 0000-0002-7313-6166
Job E LopezSection of Tropical Medicine, Department of Pediatrics, Baylor College of Medicine and Texas Children's Hospital, Houston, Texas, USA.
Jon S BlevinsDepartment of Microbiology and Immunology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA jsblevins@uams.edu.ORCID 0000-0001-6216-7365
University of Arkansas for Medical Sciences · USArkansas Children's Nutrition Center · USBaylor College of Medicine · USUniversity of Wisconsin–Madison · US

Funding

Study of the Cell-specific Inflammasome Responses During Defense Against Gram-negative BacteriaP20GM103625 · NIGMS · UNIV OF ARKANSAS FOR MED SCIS · PI SMELTZER, MARK S · 2012 to 2021
$21.5M
Pilot Grant ProgramP30GM145393 · NIGMS · UNIV OF ARKANSAS FOR MED SCIS · PI MARK S SMELTZER · 2022 to 2026
$7.6M
Identification of essential factors contributing to vector colonization and transmission of relapsing fever spirochetesR01AI137412 · NIAID · BAYLOR COLLEGE OF MEDICINE · PI LOPEZ, JOB E · 2018 to 2022
$2.0M
Identifying molecular events occurring during the life cycle of tick-born relapsing fever spirochetesR03AI123651 · NIAID · BAYLOR COLLEGE OF MEDICINE · PI LOPEZ, JOB E · 2017 to 2018
$148k
NIAID NIH HHS R01 AI137412NIAID NIH HHS R03 AI123651NIGMS NIH HHS P20 GM103625NIGMS NIH HHS P30 GM145393
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsBacterial ProteinsBorreliaCyclic AMPDisease SusceptibilityHost-Pathogen InteractionsMiceMutationPhosphorus-Oxygen LyasesRelapsing FeverSecond Messenger SystemsVirulenceBacterial ProteinsCyclic AMPPhosphorus-Oxygen LyasesBorreliaCdaAc-di-AMPcyclic-di-AMPdiadenylate cyclasedinucleotide second messengerpathogenesisrelapsing feversecond messengerTBRFtick-borne pathogenstick-borne relapsing fever

Identifiers

PMID33846120
PMCPMC8316131
OpenAlexW3156260070

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.