Evidence map›Paper›PMID 33845642›Full record

SynthesisCell transplantation

Comparison of the Efficacy and Safety of Cell-Assisted Lipotransfer and Platelet-Rich Plasma Assisted Lipotransfer: What Should We Expect from a Systematic Review with Meta-Analysis?

Aizhen Chen, Li Zhang, Penghong Chen, Chaoyu Zhang, Shijie Tang, Xiaosong Chen

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Cell transplantation. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Mesenchymal Stem Cells in Burn Wound Management.International journal of molecular sciences · 2022
    Review
  13. Article
  14. Review
  15. Hydrogels in Burn Wound Management-A Review.Gels (Basel, Switzerland) · 2022
    Review
  16. Adipose-Derived Stem Cells for Facial Rejuvenation.Journal of personalized medicine · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Aizhen ChenDepartment of Plastic Surgery, Fujian Medical University Union Hospital,   Fuzhou, Fujian, China.
Li ZhangDepartment of Central Sterile Services Department, Fujian Medical University Union Hospital, Fuzhou, Fujian, China.
Penghong ChenDepartment of Plastic Surgery, Fujian Medical University Union Hospital,   Fuzhou, Fujian, China.
Chaoyu ZhangDepartment of Plastic Surgery, Fujian Medical University Union Hospital,   Fuzhou, Fujian, China.
Shijie TangDepartment of Plastic Surgery, Fujian Medical University Union Hospital,   Fuzhou, Fujian, China.
Xiaosong ChenDepartment of Plastic Surgery, Fujian Medical University Union Hospital,   Fuzhou, Fujian, China.ORCID 0000-0002-3780-5510

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Due to the high absorption rate of traditional autologous fat grafting, cell-assisted lipotransfer (CAL) and platelet-rich plasma (PRP)-assisted lipotransfer were developed. The purpose of this article was to evaluate the efficacy and safety of CAL and PRP in promoting the survival of autologous fat grafting through systematic review and meta-analysis. We searched Pubmed, Cochrane Library, Web of Science, and EMBASE for clinical studies on CAL and PRP-assisted lipotransfer published from January 2010 to January 2020. Then a meta-analysis was performed to assess the efficacy of CAL and PRP-assisted lipotransfer through data analysis of fat survival rate. We also assessed the incidence of complications and multiple operations to analyze their safety. A total of 36 studies (1697 patients) were included in this review. Regardless of the recipient area, CAL and PRP-assisted lipotransfer significantly improved the fat survival rate (CAL vs non-CAL: 71% vs 48%,

Indexed as

Adipose TissueAdolescentAdultHumansPlatelet-Rich PlasmaYoung Adultautologous fat graftingcell-assisted lipotransfermeta-analysisplatelet-rich plasmastromal vascular fraction

Identifiers

PMID33845642
PMCPMC8058798

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.