ArticleAmerican journal of ophthalmology2021
Classification Criteria for Cytomegalovirus Anterior Uveitis.
Article in American journal of ophthalmology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
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Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Virus in infectious uveitis: bibliometric analysis and a clinical study.Frontiers in microbiology · 2025Pooled it
- Clinical performance of the multiplex solid-phase "Direct Strip PCR" for infectious uveitis: a multicenter diagnostic accuracy study.Japanese journal of ophthalmology · 2026Article
- Identifying high-risk eyes for glaucoma surgery in cytomegalovirus anterior uveitis.Scientific reports · 2026Article
- Quantitative Analysis of Background Intraocular Pressure Volatility and Retinal Nerve Fiber Layer Loss in Cytomegalovirus Anterior Uveitis.Translational vision science & technology · 2026Article
- The Use of CSF Multiplex PCR Panel in Patients with Viral Uveitis.Diagnostics (Basel, Switzerland) · 2026Article
- Efficacy of 2% ganciclovir eye drops in the treatment of cytomegalovirus anterior uveitis.Japanese journal of ophthalmology · 2025Article
- Diagnostic Performance of Universal Transport Medium for Viral Polymerase Chain Reaction in Aqueous Humor Samples of Suspected Viral Uveitis: A Pilot Methods Study.International journal of molecular sciences · 2025Article
- Machine Learning for Predicting Recurrent Course in Uveitis Using Baseline Clinical Characteristics.Investigative ophthalmology & visual science · 2025Article
- Identification of Subtypes of Herpetic Anterior Uveitis and Characterization of Their Clinical Features and Visual Outcome in a Chinese Population.Translational vision science & technology · 2025Article
- Physiological activation of liver X receptor provides protection against ocular inflammation in uveitic glaucoma.Biochimica et biophysica acta. Molecular basis of disease · 2025Article
- Identifying prognostic clues in CMV anterior uveitis: The role of corneal endothelitis and seasonal relapse patterns.Northern clinics of Istanbul · 2025Article
- In-vivo confocal microscopy predicts cytomegalovirus as the cause of chronic or recurrent anterior uveitis among Chinese.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024Article
- The Infectious Uveitis Treatment Algorithm Network (TITAN) Report 2-global current practice patterns for the management of Cytomegalovirus anterior uveitis.Eye (London, England) · 2024Article
- Artificial Intelligence in Uveitis: Innovations in Diagnosis and Therapeutic Strategies.Clinical ophthalmology (Auckland, N.Z.) · 2024Review
- Cytomegalovirus-positive Posner-Schlossman syndrome: to compare differences in retinal vessel area density between the affected and non-affected eye using optical coherence tomography angiography.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023Observational
- Comparison Between Two Types of Viral-Induced Anterior Uveitis In Vitro and In Vivo: A Stronger Response in Herpes Simplex Virus Type 1 Than in Murine Cytomegalovirus.Investigative ophthalmology & visual science · 2023Article
- The role of a multicentre data repository in ocular inflammation: The Ocular Autoimmune Systemic Inflammatory Infectious Study (OASIS).Eye (London, England) · 2023Review
- Cytomegalovirus Glycoprotein B Genotype in Patients with Anterior Segment Infection.International journal of molecular sciences · 2023Article
- A Prospective Study of Clinical Features of Anterior Uveitis in Taiwan.Journal of ophthalmology · 2023Article
- The standardisation of uveitis nomenclature (SUN) project.Clinical & experimental ophthalmology · 2022Review
Corrections and comments
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Authors and funding
1 author.
Funding
Abstract
purposeTo determine classification criteria for cytomegalovirus (CMV) anterior uveitis.
designMachine learning of cases with CMV anterior uveitis and 8 other anterior uveitides.
methodsCases of anterior uveitides were collected in an informatics-designed preliminary database, and a final database was constructed of cases achieving supermajority agreement on the diagnosis, using formal consensus techniques. Cases were split into a training set and a validation set. Machine learning using multinomial logistic regression was used on the training set to determine a parsimonious set of criteria that minimized the misclassification rate among the anterior uveitides. The resulting criteria were evaluated on the validation set.
resultsOne thousand eighty-three cases of anterior uveitides, including 89 cases of CMV anterior uveitis, were evaluated by machine learning. The overall accuracy for anterior uveitides was 97.5% in the training set and 96.7% in the validation set (95% confidence interval 92.4, 98.6). Key criteria for CMV anterior uveitis included unilateral anterior uveitis with a positive aqueous humor polymerase chain reaction assay for CMV. No clinical features reliably diagnosed CMV anterior uveitis. The misclassification rates for CMV anterior uveitis were 1.3% in the training set and 0% in the validation set.
conclusionsThe criteria for CMV anterior uveitis had a low misclassification rate and seemed to perform sufficiently well for use in clinical and translational research.
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