ArticleAmerican journal of ophthalmology2021
Classification Criteria for Sarcoidosis-Associated Uveitis.
Article in American journal of ophthalmology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 77 citations in OpenAlex.
- Presumed sarcoid choroiditis: referral pathways, demographic characteristics and disease phenotypes.Journal of ophthalmic inflammation and infection · 2026Article
- Outdated Frameworks, Missed Opportunities: A Call for Establishing Classification Criteria for Patients with Sarcoidosis.Rheumatology and therapy · 2026Review
- Advanced Multimodal Imaging in Granulomatous Uveitis: From Differential Diagnosis to Treatment Monitoring and Surgical Integration.Journal of clinical medicine · 2026Review
- Hydroxychloroquine in the treatment of sarcoidosis-associated uveitis and idiopathic uveitis.Journal of ophthalmic inflammation and infection · 2026Article
- Sarcoid Uveitis with Choroidal Involvement.Clinical ophthalmology (Auckland, N.Z.) · 2026Article
- Etiologies of intermediate uveitis in a tertiary center: an age-oriented medical assessment?Journal of ophthalmic inflammation and infection · 2025Article
- Neurosarcoidosis in Critical Care, Internal, and Pulmonary Medicine: A Practical Approach.Seminars in respiratory and critical care medicine · 2025Review
- Convolutional neural network-based differentiation of intraocular inflammatory cells with ultrahigh-resolution OCT.Biomedical optics express · 2025Article
- Concurrent uveitis in monozygotic twins in the context of systemic sarcoidosis.Journal of ophthalmic inflammation and infection · 2025Article
- The Efficacy of Adalimumab Treatment in Pediatric Non-Infectious Uveitis: A Retrospective Cohort Study.Turkish journal of ophthalmology · 2024Article
- Chronic Sarcoidosis: Diagnostic Difficulties and Search for New Criteria of Inflammatory Activity (A Case Report and Literature Review).Journal of clinical medicine · 2024Review
- Artificial Intelligence in Uveitis: Innovations in Diagnosis and Therapeutic Strategies.Clinical ophthalmology (Auckland, N.Z.) · 2024Review
- The role of a multicentre data repository in ocular inflammation: The Ocular Autoimmune Systemic Inflammatory Infectious Study (OASIS).Eye (London, England) · 2023Review
- Sarcoidosis: experience in a Mexican ophthalmological clinic.BMC ophthalmology · 2023Article
- The pattern of sarcoid uveitis at a tertiary care center in Nepal.Annals of medicine and surgery (2012) · 2023Article
- Sarcoidosis-Related Uveitis: A Review.Journal of clinical medicine · 2023Review
- The Conundrum of Clinical Trials for the Uveitides: Appropriate Outcome Measures for One Treatment Used in Several Diseases.Epidemiologic reviews · 2022Article
- The standardisation of uveitis nomenclature (SUN) project.Clinical & experimental ophthalmology · 2022Review
- Management of Non-Infectious Uveitis, a Selection of Topical Items Updating.Journal of clinical medicine · 2022Article
- Subretinal peripapillary biopsy-proven sarcoidosis: a case report.International journal of retina and vitreous · 2022Article
Corrections and comments
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Authors and funding
1 author.
Funding
Abstract
purposeThe purpose of this study was to determine classification criteria for sarcoidosis-associated uveitis.
designMachine learning of cases with sarcoid uveitis and 15 other uveitides.
methodsCases of anterior, intermediate, and panuveitides were collected in an informatics-designed preliminary database, and a final database was constructed including cases achieving supermajority agreement on the diagnosis, using formal consensus techniques. Cases were analyzed by anatomic class, and each class was split into a training set and a validation set. Machine learning using multinomial logistic regression was used in the training sets to determine a parsimonious set of criteria that minimized the misclassification rate among the uveitides. The resulting criteria were evaluated in the validation sets.
resultsA total of 1,083 cases of anterior uveitides, 589 cases of intermediate uveitides, and 1,012 cases of panuveitides, including 278 cases of sarcoidosis-associated uveitis, were evaluated by machine learning. Key criteria for sarcoidosis-associated uveitis included a compatible uveitic syndrome of any anatomic class and evidence of sarcoidosis, either 1) tissue biopsy results demonstrating non-caseating granulomata or 2) bilateral hilar adenopathy on chest imaging. The overall accuracy of the diagnosis of sarcoidosis-associated uveitis in the validation set was 99.7% (95% confidence interval: 98.8-99.9). The misclassification rates for sarcoidosis-associated uveitis in the training sets were 3.2% in anterior uveitis, 2.6% in intermediate uveitis, and 1.2% in panuveitis; in the validation sets, the misclassification rates were 0% in anterior uveitis, 0% in intermediate uveitis, and 0% in panuveitis.
conclusionsThe criteria for sarcoidosis-associated uveitis had a low misclassification rate and appeared to perform sufficiently well for use in clinical and translational research.
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