Evidence map›Paper›PMID 33844845›Full record

ArticleInternational journal of cancer2021

Red meat consumption, cooking mutagens, NAT1/2 genotypes and pancreatic cancer risk in two ethnically diverse prospective cohorts.

Brian Z Huang, Songren Wang, David Bogumil, Lynne R Wilkens, Lang Wu, William J Blot, Wei Zheng, Xiao-Ou Shu, Stephen J Pandol, Loïc Le Marchand and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in International journal of cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 4 pooled it
1.3field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 4 syntheses or guidelines pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Brian Z HuangDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.ORCID https://orcid.org/0000-0001-8645-5142
Songren WangDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
David BogumilDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
Lynne R WilkensEpidemiology Program, University of Hawaii Cancer Center, Honolulu, Hawaii, USA.
Lang WuEpidemiology Program, University of Hawaii Cancer Center, Honolulu, Hawaii, USA.
William J BlotDivision of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Wei ZhengDivision of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Xiao-Ou ShuDivision of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Stephen J PandolDivision of Gastroenterology, Department of Medicine, Cedars-Sinai Medical Center and Department of Veterans Affairs, Los Angeles, California, USA.
Loïc Le MarchandEpidemiology Program, University of Hawaii Cancer Center, Honolulu, Hawaii, USA.
Veronica Wendy SetiawanDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
University of Southern California · USUniversity of Hawaiʻi at Mānoa · USVanderbilt University Medical Center · USCedars-Sinai Medical Center · US

Funding

Understanding Population Differences in Cancer: The MEC StudyU01CA164973 · NCI · UNIVERSITY OF HAWAII AT MANOA · PI HAIMAN, CHRISTOPHER ALAN, LE MARCHAND, LOIC · 2015 to 2025
$37.4M
Southern Community Cohort StudyU01CA202979 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BLOT, WILLIAM J., SHRUBSOLE, MARTHA J. · 2016 to 2025
$22.0M
Project 3: Role of the pancreatic fibroinflammatory microenvironment in obesity-promoted pancreatic cancerP01CA236585 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI GO, VAY LIANG W · 2020 to 2024
$5.6M
Multidisciplinary Training in Ethnic Diversity and Cancer DisparitiesT32CA229110 · NCI · UNIVERSITY OF HAWAII AT MANOA · PI HAIMAN, CHRISTOPHER ALAN, LE MARCHAND, LOIC · 2019 to 2023
$2.1M
Investigating the cause of racial/ethnic disparity in pancreatic cancer incidenceR01CA209798 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI SETIAWAN, VERONICA WENDY · 2017 to 2020
$1.8M
Integrating epidemiologic, clinical, genomic and metabolomic profiles to predict pancreatic cancer risk in a multiethnic populationK99CA256525 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI HUANG, BRIAN · 2021 to 2022
$240k
American Cancer Society RSG-16-250-01-CPHPSNCI NIH HHS K99 CA256525NCI NIH HHS K99CA256525NCI NIH HHS P01 CA236585NCI NIH HHS R01 CA209798NCI NIH HHS R01CA209798NCI NIH HHS T32 CA229110NCI NIH HHS T32CA229110NCI NIH HHS U01 CA164973NCI NIH HHS U01CA164973NCI NIH HHS U01 CA202979NCI NIH HHS U01CA202979
6 · The paper itself

Abstract

There is limited evidence on the association between red meat consumption and pancreatic cancer among ethnic minorities. We assessed this relationship in two large prospective cohorts: the Multiethnic Cohort Study (MEC) and the Southern Community Cohort Study (SCCS). Demographic, dietary and other risk factor data were collected at cohort entry. Red meat intake was assessed using cohort-specific validated food frequency questionnaires. Incident pancreatic cancer cases were identified via linkages to state cancer registries. Cox regression was used to calculate relative risks (RRs) and 95% confidence intervals (CIs) for the association of red meat intake with pancreatic cancer risk in each cohort. We performed additional analyses to evaluate cooking methods, mutagens and effect modification by NAT1/2 genotypes. From a total of 184 542 (MEC) and 66 793 (SCCS) at-risk participants, we identified 1618 (MEC) and 266 (SCCS) incident pancreatic cancer cases. Red meat consumption was associated with pancreatic cancer risk in the MEC (RR

Indexed as

cohortdietepidemiologypancreatic ductal adenocarcinoma

Identifiers

PMID33844845
PMCPMC8594451
OpenAlexW3155072908

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.