Evidence map›Paper›PMID 33844598›Full record

ArticleEnvironmental health perspectives2021

Long-Term Exposure to Fine Particle Elemental Components and Natural and Cause-Specific Mortality-a Pooled Analysis of Eight European Cohorts within the ELAPSE Project.

Jie Chen, Sophia Rodopoulou, Kees de Hoogh, Maciej Strak, Zorana J Andersen, Richard Atkinson, Mariska Bauwelinck, Tom Bellander, Jørgen Brandt, Giulia Cesaroni and 40 more

Abstract read
In one paragraph

Article in Environmental health perspectives, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Long-Term Exposure to Low-LevelEnvironmental health perspectives · 2023
    Pooled it
  2. Pooled it
  3. Observational
  4. Mitigating indoor risk of airborne infections using COJournal of environmental health science & engineering · 2026
    Article
  5. Article
  6. Article
  7. Review
  8. The role of the components of PMEnvironment international · 2025
    Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Review
  17. Article
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

50 authors.

Jie ChenInstitute for Risk Assessment Sciences, Utrecht University, Utrecht, Netherlands.
Sophia RodopoulouDepartment of Hygiene, Epidemiology and Medical Statistics, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
Kees de HooghSwiss Tropical and Public Health Institute, Basel, Switzerland.
Maciej StrakInstitute for Risk Assessment Sciences, Utrecht University, Utrecht, Netherlands.
Zorana J AndersenSection of Environmental Health, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.
Richard AtkinsonPopulation Health Research, St George's, University of London, London, UK.
Mariska BauwelinckInterface Demography, Department of Sociology, Vrije Universiteit Brussel, Brussels, Belgium.
Tom BellanderInstitute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Jørgen BrandtDepartment of Environmental Science, Aarhus University, Denmark.
Giulia CesaroniDepartment of Epidemiology, Lazio Region Health Service, Rome, Italy.
Hans ConcinAgency for Preventive and Social Medicine, Bregenz, Austria.
Daniela FechtMedical Research Council Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.
Francesco ForastiereDepartment of Epidemiology, Lazio Region Health Service, Rome, Italy.
John GulliverMedical Research Council Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.
Ole HertelDepartment of Environmental Science, Aarhus University, Denmark.
Barbara HoffmannInstitute for Occupational, Social and Environmental Medicine, Centre for Health and Society, Medical Faculty, Heinrich Heine University Düsseldorf, Germany.
Ulla Arthur HvidtfeldtDanish Cancer Society Research Center, Copenhagen, Denmark.
Nicole A H JanssenNational Institute for Public Health and the Environment, Bilthoven, Netherlands.
Karl-Heinz JöckelInstitute for Medical Informatics, Biometry and Epidemiology, Medical Faculty, University of Duisburg-Essen, Essen, Germany.
Jeanette JørgensenSection of Environmental Health, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.
Klea KatsouyanniDepartment of Hygiene, Epidemiology and Medical Statistics, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
Matthias KetzelDepartment of Environmental Science, Aarhus University, Denmark.
Jochem O KlompmakerNational Institute for Public Health and the Environment, Bilthoven, Netherlands.
Anton LagerDepartment of Global Public Health, Karolinska Institutet, Stockholm, Sweden.
Karin LeanderInstitute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Shuo LiuSection of Environmental Health, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.
Petter LjungmanInstitute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Conor J MacDonaldCentre de recherche en Epidémiologie et Santé des Populations, Faculté de Medicine, Université Paris-Saclay, Villejuif, France.
Patrik K E MagnussonDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Amar MehtaSection of Epidemiology, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.
Gabriele NagelInstitute of Epidemiology and Medical Biometry, Ulm University, Ulm, Germany.
Bente OftedalDepartment of Environmental Health, Norwegian Institute of Public Health, Oslo, Norway.
Göran PershagenInstitute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Annette PetersInstitute of Epidemiology, Helmholtz Zentrum München, Neuherberg, Germany.
Ole Raaschou-NielsenDanish Cancer Society Research Center, Copenhagen, Denmark.
Matteo RenziDepartment of Epidemiology, Lazio Region Health Service, Rome, Italy.
Debora RizzutoDepartment of Neurobiology, Care Sciences, and Society, Karolinska Institutet, Stockholm, Sweden.
Evangelia SamoliDepartment of Hygiene, Epidemiology and Medical Statistics, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
Yvonne T van der SchouwJulius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands.
Sara SchrammInstitute for Medical Informatics, Biometry and Epidemiology, Medical Faculty, University of Duisburg-Essen, Essen, Germany.
Per SchwarzeDepartment of Environmental Health, Norwegian Institute of Public Health, Oslo, Norway.
Torben SigsgaardDepartment of Public Health, Section of Environment Occupation and Health, Danish Ramazzini Centre, Aarhus University, Aarhus, Denmark.
Mette SørensenDanish Cancer Society Research Center, Copenhagen, Denmark.
Massimo StafoggiaInstitute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Anne TjønnelandDanish Cancer Society Research Center, Copenhagen, Denmark.
Danielle VienneauSwiss Tropical and Public Health Institute, Basel, Switzerland.
Gudrun WeinmayrInstitute of Epidemiology and Medical Biometry, Ulm University, Ulm, Germany.
Kathrin WolfInstitute of Epidemiology, Helmholtz Zentrum München, Neuherberg, Germany.
Bert BrunekreefInstitute for Risk Assessment Sciences, Utrecht University, Utrecht, Netherlands.
Gerard HoekInstitute for Risk Assessment Sciences, Utrecht University, Utrecht, Netherlands.

Funding

Medical Research Council MR/S019669/1
6 · The paper itself

Abstract

backgroundInconsistent associations between long-term exposure to particles with an aerodynamic diameter

objectivesWe investigated the associations between long-term exposure to

methodsWe pooled data from eight European cohorts with 323,782 participants, average age 49 y at baseline (1985-2005). Residential exposure to 2010 annual average concentration of eight

resultsWe observed 46,640 natural-cause deaths with 6,317,235 person-years and an average follow-up of 19.5 y. All SLR-modeled components were statistically significantly associated with natural-cause mortality in single-pollutant models with hazard ratios (HRs) from 1.05 to 1.27. Similar HRs were observed for RF-modeled Cu, Fe, K, S, V, and Zn with wider confidence intervals (CIs). HRs for SLR-modeled Ni, S, Si, V, and Zn remained above unity and (almost) significant after adjustment for both

conclusionLong-term exposure to V in

Indexed as

Air PollutantsAir PollutionCause of DeathCohort StudiesEnvironmental ExposureHumansMiddle AgedParticulate MatterAir PollutantsParticulate Matter

Identifiers

PMID33844598
PMCPMC8041432

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.