Evidence map›Paper›PMID 33844300›Full record

ArticleAlcoholism, clinical and experimental research2021

The association of alcohol use with all-cause and cardiovascular disease-related hospitalizations or death in older, high-risk Veterans.

Dan V Blalock, Janet Grubber, Valerie A Smith, Donna M Zulman, Hollis J Weidenbacher, Liberty Greene, Eric A Dedert, Matthew L Maciejewski

Open access · greenAbstract read
In one paragraph

Article in Alcoholism, clinical and experimental research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Dan V BlalockDurham Center of Innovation to Accelerate Discovery and Practice Transformation (ADAPT, Durham Veterans Affairs Health Care System, Durham, NC, USA.ORCID 0000-0002-8349-9825
Janet GrubberDurham Center of Innovation to Accelerate Discovery and Practice Transformation (ADAPT, Durham Veterans Affairs Health Care System, Durham, NC, USA.
Valerie A SmithDurham Center of Innovation to Accelerate Discovery and Practice Transformation (ADAPT, Durham Veterans Affairs Health Care System, Durham, NC, USA.
Donna M ZulmanCenter for Innovation to Implementation, VA Palo Alto Health Care System, Menlo Park, CA, USA.
Hollis J WeidenbacherDurham Center of Innovation to Accelerate Discovery and Practice Transformation (ADAPT, Durham Veterans Affairs Health Care System, Durham, NC, USA.
Liberty GreeneCenter for Innovation to Implementation, VA Palo Alto Health Care System, Menlo Park, CA, USA.
Eric A DedertDepartment of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC, USA.
Matthew L MaciejewskiDurham Center of Innovation to Accelerate Discovery and Practice Transformation (ADAPT, Durham Veterans Affairs Health Care System, Durham, NC, USA.
Duke University · USDurham VA Health Care System · USVA Palo Alto Health Care System · US

Funding

Support for QA/QC for Prior Approval ProcessUL1TR002553 · NCATS · DUKE UNIVERSITY · PI LI, JENNIFER S, MCNAMARA, JAMES O. · 2018 to 2023
$58.5M
Resource Core 3 - Metabolomics CoreP30AG028716 · NIA · DUKE UNIVERSITY · PI CATHLEEN S COLON-EMERIC, Susan Nicole Hastings · 2006 to 2026
$24.6M
Preparing For What Is Next With Aducanumab In Real World SettingsR33AG057806 · NIA · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI Christopher Barrett Bowling, Ana Roman Quinones · 2018 to 2026
$9.0M
Physical Resiliencies: Indicators and Mechanisms in the Elderly CollaborativeUH3AG056925 · NIA · DUKE UNIVERSITY · PI COLON-EMERIC, CATHLEEN S · 2019 to 2021
$4.6M
HSRD VA IK2 HX003085HSRD VA IK6 HX003157NCATS NIH HHS UL1 TR002553NIA NIH HHS P30 AG028716NIA NIH HHS R33 AG057806NIA NIH HHS UH3 AG056925NIH HHS P30AG028716NIH HHS R33AG057806NIH HHS UH3 AG056925NIH HHS UL1TR002553U.S. Department of Veterans Affairs RCS 10-391
6 · The paper itself

Abstract

backgroundThe prevalence of alcohol misuse among older adults has grown dramatically in the past decade, yet little is known about the association of alcohol misuse with hospitalization and death in this patient population.

methodsWe examined the association between alcohol use (measured by a screening instrument in primary care) and rates of all-cause and cardiovascular disease (CVD)-related 6-month hospitalization or death via electronic health records (EHRs) in a nationally representative sample of older, high-risk Veterans. Models were adjusted for sociodemographic and clinical characteristics, including frailty and comorbid conditions.

resultsThe all-cause hospitalization or death rate at 6 months was 14.9%, and the CVD-related hospitalization or death rate was 1.8%. In adjusted analyses, all-cause hospitalization or death was higher in older Veterans who were nondrinkers or harmful use drinkers compared to moderate use drinkers, but CVD-related hospitalization or death was similar in all categories of drinking.

conclusionsThese findings suggest that the complex association between alcohol and all-cause acute healthcare utilization found in the broader population is similar in older, high-risk Veteran patients. These findings do not support an association between alcohol consumption and CVD-specific hospitalizations.

Indexed as

AdultAgedAged, 80 and overAlcohol DrinkingCardiovascular DiseasesCross-Sectional StudiesFemaleHospitalizationHumansMaleMiddle AgedUnited StatesVeteransalcoholcardiovascular diseasehospitalizationsscreeningVeterans

Identifiers

PMID33844300
PMCPMC9062788
OpenAlexW3156767299

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.